Results 171 to 180 of about 8,474,282 (288)

Positive B cell flow cytometry crossmatch without detectable donor-specific antibodies: true or false reactivity? [PDF]

Front Immunol
de Chickera SN, Al Agbar S, Sharma A, Beaune D, Sidahmed EA, Gunaratnam L, Sidahmed A.   +6 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Preformed donor-specific antibodies are associated with acute rejection and biliary complications after liver transplantation: A Swiss Transplant Cohort Study analysis. [PDF]

Liver Transpl
Vionnet J, Ferrari-Lacraz S, Hoessly LD, Mancarella A, Müller YD, Schaub S, Nilsson J, Wirthmüller U, Stampf S, Koller M, Mueller NJ, Amrari M, Manuel O, Golshayan D, Fraga M, Moradpour D, Goossens N, Magini G, Compagnon P, McLin V, Rock N, Wildhaber B, Kremer AE, Oberholzer J, Sousa Da Silva RX, Tinguely P, Kavaliukaite L, Berzigotti A, Banz V, Bernsmeier C, Dutkowski P, Semela D, Niemann M, Pantaleo G, Pascual M, Villard J, and the Swiss Transplant Cohort Study (STCS).   +36 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Effect of preexisting human leukocyte antigen donor-specific antibodies especially human leukocyte antigen-DQ on kidney transplant outcome. [PDF]

Front Nephrol
Mehrotra S, Sharma RK, Kapoor R, Jaiswal RK, Kapoor R.   +4 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Management of donor-specific antibodies in allogeneic hematopoietic cell transplantation: A retrospective single-center case-control study. [PDF]

Cell Transplant
Harland L, Schüch SL, Katzenstein S, Hammer S, Faul C, Althaus K, Bohnert BN, Löffler MW, Bakchoul T, Lengerke C, Bethge WA.   +10 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

HLA-DQ7 De Novo Donor-Specific Antibodies Are Associated with Increased Risk of Chronic Lung Allograft Dysfunction After Lung Transplantation. [PDF]

J Clin Med
Vorstandlechner M, Walter J, Schneider CP, Samm N, Michel S, Arnold P, Tomasi R, Dick A, Kauke T.   +8 more
europepmc   +1 more source