Results 181 to 190 of about 135,445 (284)

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

Advanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He, Anqi Zhang, Zhanchen Guo, Qi Li, Song Gao, Wenyan Guan, Ying Li, Jingran Chen, Sijia Sun, Jian He, Zhen Liu   +10 more
wiley   +1 more source

SR‐B1‐Mediated Transplacental Transfer of Hydrophobic Toxicants Disrupts Fetal Development During Barriergenesis

Advanced Science, EarlyView.
This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang, Hailin Shang, Ling Jiao, Ce Chen, Zehua Liu, Yi Yang, Qiannan Zhang, Song Tang, Xudong Jia, Hui Yang, Yi Wan   +10 more
wiley   +1 more source

Ultraviolet-C Treatment Better Preserves the Proteomic Profile of Donor Human Milk than Holder Pasteurization. [PDF]

J Agric Food Chem
Kim BJ, Ryan MB, Dallas DC.
europepmc   +1 more source

Supplementation of mother's own milk with term versus preterm donor human milk: a randomized controlled trial. [PDF]

Eur J Pediatr, 2023
Soni V, Jain S, Chawla D, Khurana S, Rani S.   +4 more
europepmc   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Donor human milk storage and gastrointestinal morbidities in preterm infants: A case-control study. [PDF]

JPEN J Parenter Enteral Nutr
Camilon TJM, Galemmo M, Savino W, Rohrer A, Gregoski MJ, Lesher AP, Chetta KE.   +6 more
europepmc   +1 more source

Preterm Pigs Fed Donor Human Milk Have Greater Liver β-Carotene Concentrations than Pigs Fed Infant Formula. [PDF]

J Nutr, 2023
Moran NE, Wade J, Stroh R, Stoll B, Guthrie G, Hair AB, Burrin DG.   +6 more
europepmc   +1 more source

Cyclosporine and its metabolites in mother and baby [PDF]

, 1988
Burckart, GJ, Caritis, SN, Koneru, B, Paul Wang, CC, Starzl, TE, Venkataramanan, R   +5 more
core   +1 more source

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

Advanced Science, EarlyView.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz, Maria Odenthal‐Schnittler, Jan Philip Kipcke, Jochen Seebach, Zahra Labbaf, Franziska Merten, Vesna Bojovic, Muna Taha, Johannes A. Eble, Erez Raz, Milos Galic, Hans Schnittler   +11 more
wiley   +1 more source

Effects of Donor Human Milk and Formula Supplementation on Bone Metabolism and Clinical Outcomes in Preterm Infants Receiving Mother's Own Milk. [PDF]

Nutrients
Herzlich J, Frumer B, Mandel D, Morag S, Halperin A, Mangel L.   +5 more
europepmc   +1 more source