Results 201 to 210 of about 90,955 (259)
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development
Advanced Science, EarlyView.The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao +9 more
wiley +1 more source
Time to Step-Up Our Game Concerning Nutrient Analysis of Pasteurized Donor Human Milk?
Deborah L. O’Connor
openalex +1 more source
Construction of Large‐Scale Bioengineered Hair Germs and In Vivo Transplantation
Advanced Science, EarlyView.Here, a novel bioengineered hair germ (BHG) system is developed using thermodynamically incompatible mucopolysaccharides for efficient hair follicle regeneration. The BHG microspheres, produced via microfluidic technology, encapsulate Wnt3a for sustained release, enhancing mesenchymal stem cell differentiation and activating key regeneration pathways ...
Yangpeng Chen +8 more
wiley +1 more source
Determinants of human milk donation: data from women donors at a milk bank
Thayne Alexandre de Carvalho +1 more
openalex +1 more source
Advanced Science, EarlyView.Engineered microarrays are prepared by the photolithography and further decorated via fibronectin protein to determine the morphogenesis of stem cells. Heterogeneous integrin expression and focal adhesion formation are regulated in microarrayed cells. Polar remodeling of cytoskeleton nanomechanics happens in the heterogeneous cells.
Nana Wang +10 more
wiley +1 more source
Advanced Science, EarlyView.This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microbubble‐assisted UltraSound‐guided Immunotherapy of Cancer (MUSIC), this strategy effectively inhibits tumor growth and improves survival in mouse models of ...
Sina Khorsandi +12 more
wiley +1 more source
MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue
Advanced Science, EarlyView.This study demonstrates that MTCH2 acts as an evolutionarily conserved regulator of energy homeostasis across Drosophila, rodents, and humans. Adipose‐specific MTCH2 ablation enhances brown/beige adipose thermogenesis through Bcl‐2‐dependent autophagy, promoting energy expenditure and counteracting obesity‐associated metabolic disorders. These findings
Xin‐Yuan Zhao +17 more
wiley +1 more source