Results 241 to 250 of about 134,638 (291)

Profiles of commensal and opportunistic bacteria in human milk from healthy donors in Taiwan

, 2018
Po‐Wen Chen, Yi-Ling Lin, Maosheng Huang   +2 more
openalex   +1 more source

Methionine Metabolism Dictates PCSK9 Expression and Antitumor Potency of PD‐1 Blockade in MSS Colorectal Cancer

Advanced Science, EarlyView.
xxxx. Abstract Nutrient metabolisms are vitally interrelated to cancer progression and immunotherapy. However, the mechanisms by which nutrient metabolisms interact to remodel immune surveillance within the tumor microenvironment remain largely unexplored.
Qi‐Long Wang, Zijie Chen, Xiaofei Lu, Huizhen Lin, Huolun Feng, Nuozhou Weng, Liwen Chen, Mengnan Liu, Li Long, Lingjun Huang, Yongmei Deng, Kehong Zheng, Xiaojun Zheng, Yong Li, Ting Cai, Jiabin Zheng, Wei Yang   +16 more
wiley   +1 more source

Efficacy of Pasteurised Donor Human Milk on the Growth of Preterm Neonates: A Research Protocol of a Randomised Control Trial

Akansha Sisodia, Revat Meshram, Sagar Karotkar   +2 more
openalex   +1 more source

SUMOylation of SETD8 Promotes Tumor Growth by Methylating and Stabilizing MYC in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer (BC), MYC serves as a novel substrate of SETD8 to be methylated at lysine 412, which enhances MYC protein stability by preventing the CHIP‐mediated degradation and ultimately promotes tumor growth. SUMOylation of SETD8 leads to SETD8 stabilization and enhances MYC methylation.
Xia Zhang, Zhenxuan Chen, Xiaobo He, Jingxuan Wang, Jianliang Zhong, Yezi Zou, Xianchong Zheng, Yujie Lin, Ruhua Zhang, Tiebang Kang, Liwen Zhou, Yuanzhong Wu   +11 more
wiley   +1 more source

Hygienic-sanitary quality of donated human milk in terms of the donor profile and pumping site

Ana Carolina de Prima Souza, Ana Carolina Lavio Rocha, Lucíola Sant’Anna de Castro, Bárbara Tideman Sartório Camargo, Rosana Rodrigues Figueira Fogliano, Miriam Harumi Tsunemi, Kelly Pereira Coca   +6 more
openalex   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

Advanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan, Jingyi Qi, Yi Xia, Chang Fan, Teng Xu, Xu Zhang, Jiaxin Shi, Chenxuan Wang, Yitong Cheng, Dongyuan Zhang, Rong Liu, Yinhua Zhu, Changchang Cao, Dekui Jin, Peng An, Yongting Luo, Junjie Luo   +16 more
wiley   +1 more source

Structured lactation support for mothers of very low birthweight preterm infants and establishment of human donor milk banks in German NICUs (Neo-MILK): protocol for a hybrid type 1 effectiveness-implementation cluster-randomised controlled trial

Nicola Gabriela Dymek, Julia Jaschke, Anna Katharina Stirner, Isabella Schwab, Tim Ohnhäuser, Daniel Wiesen, Till Dresbach, Nadine Scholten, Juliane Köberlein–Neu   +8 more
openalex   +1 more source

ELECTROLYTE AND MINERAL COMPOSITION OF TERM DONOR HUMAN MILK BEFORE AND AFTER PASTEURIZATION AND OF RAW MILK OF PRETERM MOTHERS

, 2018
Carla Regina Bianchi Codo, Jamil Pedro de Siqueira Caldas, Rafaella Regina Alves Peixoto, Vitor L. Sanches, Tamara Cristina Guiraldelo, Solange Cadore, Sérgio Tadeu Martins Marba   +6 more
openalex   +2 more sources

Macrophage WEE1 Directly Binds to and Phosphorylates NF‐κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis

Advanced Science, EarlyView.
The present study shows that macrophage WEE1 drives NF‐κB activation and inflammatory atherosclerosis by directly phosphorylating p65 at S536. This finding illustrates a macrophage‐specific WEE1‐p65 axis in regulating inflammatory atherosclerosis and points out new directions to broaden the clinical applications for WEE1 inhibitors in atherosclerosis ...
Zhuqi Huang, Sirui Shen, Weixin Li, Mengyang Wang, Yudie Yang, Wu Luo, Xue Han, Zheng Xu, Julian Min, Xiaohong Long, Weijian Huang, Gaojun Wu, Yi Wang, Guang Liang   +13 more
wiley   +1 more source

An in vitro batch culture study to assess the fermentation of human milk oligosaccharides by faecal microbiota from healthy and irritable bowel syndrome stool donors

Patricia Sanz Morales, Anisha Wijeyesekera, Masumi Robertson, Giles Major, Claire L. Boulangé, Peter Philip James Jackson, Carlos Turrado, G.R. Gibson   +7 more
openalex   +1 more source