Results 241 to 250 of about 211,043 (288)

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

Advanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu, Yi Shi, Chao‐Hua Kong, Ai‐Qun Chen, Ying Kang, Jun‐Yan Kan, Xiao‐Min Jiang, Peng Chu, Dong‐Chen Wang, Yi‐Fei Lv, Zhi‐Yuan Qian, Zi‐Hao Jiang, Yun‐Wei Chen, Yue Sun, Rui‐Rui Chang, Wen‐Ying Zhou, Yue Gu, Jun‐Xia Zhang, Shao‐Liang Chen   +18 more
wiley   +1 more source

Impact of diet and body composition on donor human milk: a cross-sectional pilot study

Sara Lopes da Silva, Beatriz Teixeira, Susana Pissarra, Sónia Fraga, Rita Moita, Henrique Soares, Cristina Martins, Cláudia Camila Dias, Diana e Silva   +8 more
openalex   +1 more source

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

Does Pasteurized Donor Human Milk Provide Adequate Intakes of Minerals and Trace Elements for Term-Born Infants?

Megan R. Beggs, K. Patton, Meghan B. Azad, Debbie Stone, Michael A. Pitino, Sharon Unger, Deborah O’Connor   +6 more
openalex   +1 more source

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

Advanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li, Xinzhu Li, Xiao Xiang, Jundong Huang, Xinyu Shen, Mengyue Wang, Jingwei Jiang, Shiwen Shao, Zeming Li, Tian Xie, Deming Liu, Yiping Zhao, Rui Ma, Wenyu Wu, Wei Shi, Cheng‐Ming Chuong, Ji Li, Mingxing Lei   +17 more
wiley   +1 more source

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The Current State of Donor Human Milk Use and Practice.

Journal of Midwifery & Women's Health, 2021
Human milk contains nutrients and immune factors that promote health and growth of an infant. Donor human milk is recommended as the best alternative for infants whose mothers' breast milk is unavailable.
Yeon K. Bai, J. Kuscin
semanticscholar   +4 more sources

Pooling Strategies to Modify Macronutrient Content of Pasteurized Donor Human Milk.

Breastfeeding Medicine, 2023
Background: Donor human milk (DHM) is the recommended feeding for preterm infants when mother's own milk is unavailable or insufficient. DHM macronutrient's variability may have significant implications on preterm growth.
C. Tabasso, P. Piemontese, Nicola Pesenti, M. Perrone, Camilla Menis, N. Liotto, O. Amato, A. Orsi, D. Mallardi, F. Mosca, P. Roggero   +10 more
semanticscholar   +1 more source

Macronutrient content of pasteurised donor human milk: Variability between batches from single‐donor pools at an Australian milk bank

Journal of Paediatrics and Child Health, 2023
This study aimed to characterise the between‐batch variability of pasteurised donor human milk (PDHM) produced from single‐donor pools at Australian Red Cross Lifeblood's milk bank and identify key donor characteristics that predict macronutrient content.
Leonie Walter, Vanessa Clifford, Christine Sulfaro, Richard Brown, Daniel Ribeiro, Marijke Welvaert, Glen Shuttleworth, Laura D. Klein   +7 more
semanticscholar   +1 more source

Microbiological Screening of Donor Human Milk

Breastfeeding Medicine, 2023
Mother's own milk is recognized as the optimal feeding not only for term but also for preterm infants. In addition to risk reduction for sepsis, necrotizing enterocolitis, bronchopulmonary dysplasia, and retinopathy of prematurity in the early infancy, feeding preterm infants with mother's own milk is also associated with a better neurodevelopmental ...
Christine Schreiner, Andreas Müller, Till Dresbach   +2 more
openaire   +2 more sources