Results 81 to 90 of about 132,714 (327)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

“Mothers knowledge and attitude on feeding of banked human milk among infants” with view to develop an information booklet”

Indian Journal of Health Sciences and Biomedical Research KLEU, 2021
INTRODUCTION: Donor breastfeeding is the best natural feeding. Especially in high-risk and preterm infants, donor breast milk is the best source of nutrition.
Hussainbi A Tahasildar, Gavishiddhayya B Salimath   +1 more
doaj   +1 more source

Effects of preconditioning and extrusion of linseed on the ruminal biohydrogenation of fatty acids. 2. In vitro and in situ studies [PDF]

, 2006
The extent and/or intermediates of ruminal biohydrogenation (BH) of fatty acids (FA) were investigated in vitro and in situ using a raw, pre-conditioned or extruded blend of linseed and wheat bran (70:30).
Akraim, Fowad, Enjalbert, Francis, Nicot, Marie-Claude, Weill, P.   +3 more
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

The global status of human milk banking

Maternal and Child Nutrition
Human milk provides essential nutrition for infants and holds many health benefits for infants and mothers. When a mother's own milk is not available for her infant, the World Health Organization recommends feeding donor human milk (DHM) from a human ...
Kiersten Israel‐Ballard, Emily LaRose, Kimberly Mansen   +2 more
doaj   +1 more source

A report on operating a nationwide human milk bank in Korea [PDF]

, 2010
Purpose : A human milk bank collects, processes, eliminates, and stores breast milk from donors and provides breast milk to those in need. The authors hereby present the experiences and the objective lessons obtained through operating a nationwide human ...
Chong-Woo Bae, Committee on Health Care for Underserved Women, Eun Young Park, Gartner, Hartmann, Ji Young Chang, Kang Hoon Song, Lawrence, Lording, McGuire, Nam Kyu Cho, Omarsdottir, Schanler, Sung Ae Park, Yoo Min Lee   +14 more
core   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

The evidence for the benefits from breast milk in the neurodevelopment of premature babies – a review of the recent literature [PDF]

, 2018
Introduction. The brain in preterm babies is usually not fully developed and therefore early post-term events can have long-lasting neurodevelopment and cognitive outcomes. It is known that cerebral white matter connectivity is important for later intact
Paduraru, Danuta Iulia
core   +1 more source

Growth factor restriction impedes progression of wound healing following cataract surgery: identification of VEGF as a putative therapeutic target [PDF]

, 2016
Secondary visual loss occurs in millions of patients due to a wound-healing response, known as posterior capsule opacification (PCO), following cataract surgery. An intraocular lens (IOL) is implanted into residual lens tissue, known as the capsular bag,
A Parenti, AJ Maloof, B Amoozgar, B Hinz, B Lundqvist, B Thylefors, BP Danysh, C Biagi, D Belotti, D Spalton, D Xu, G Duncan, G Duncan, GC Brown, IM Wormstone, IM Wormstone, IM Wormstone, IM Wormstone, IM Wormstone, J Nagata, JA Eldred, JA Eldred, JF Boyce, JL Davis, JL Kovach, K Hayashi, K Ohta, L Leishman, MA Nanavaty, N Ferrara, NI Chaudhary, NV Palejwala, O Nishi, PJ Sime, R Alon, RJ Kelly, RL Avery, RU de Iongh, S Resnikoff, SC Kavoussi, T Hara, T Hara, TM Rabsilber, W Wu, X Huang   +44 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source