Clinics, 2012 OBJECTIVE: The significance of pretransplant, donor-specific antibodies on long-term patient outcomes is a subject of debate. This study evaluated the impact and the presence or absence of donor-specific antibodies after kidney transplantation on short ...
Elias David-Neto +10 more
doaj +2 more sources
De Novo Donor-Specific Antibodies after Heart Transplantation: A Comprehensive Guide for Clinicians [PDF]
J Clin Med, 2023 Antibodies directed against donor-specific human leukocyte antigens (HLAs) can be detected de novo after heart transplantation and play a key role in long-term survival.
María Dolores García-Cosío Carmena +23 more
core +2 more sources
Indian Journal of TransplantationThe use of posttransplant cyclophosphamide has revolutionized the field of haploidentical hematopoietic stem cell transplant. The impact has been especially enhanced in low- and middle-income countries. Unrelated donor pool in developing nations is often
Rohit Kapoor +7 more
doaj +2 more sources
The role of C4d and donor specific antibodies in face and hand transplantation—a systematic review [PDF]
Frontiers in TransplantationTo date, little is known about the mechanisms of rejection in vascularized composite allotransplantation, particularly for antibody mediated rejection.
Lioba Huelsboemer +15 more
doaj +2 more sources
An adjustable predictive score of graft survival in kidney transplant patients and the levels of risk linked to de novo donor-specific anti-HLA antibodies. [PDF]
PLoS ONE, 2017 Most predictive models and scores of graft survival in renal transplantation include factors known before transplant or at the end of the first year. They cannot be updated thereafter, even in patients developing donor-specific anti-HLA antibodies and ...
Aurélie Prémaud +8 more
doaj +2 more sources
Re-Evaluating the Transplant Glomerulopathy Lesion—Beyond Donor-Specific Antibodies [PDF]
Transplant InternationalThere have been significant advances in short-term outcomes in renal transplantation. However, longer-term graft survival has improved only minimally.
Arun Chutani +3 more
doaj +2 more sources
Early posttransplant rituximab use in kidney transplant recipients with preexisting donor-specific antibodies [PDF]
Renal FailureThe presence of pretransplant anti-human leukocyte antigen (HLA) donor-specific antibodies (DSAs) is still a significant barrier to successful kidney transplantation, as it increases the risk of rejection and graft failure. Rituximab (anti-CD20 antibody)
Junji Yamauchi +9 more
doaj +2 more sources
Beyond Donor-Specific Antibodies: The Unseen Role of Non-Donor-Specific Anti-human Leukocyte Antigen (HLA) Antibodies in Rejection [PDF]
CureusAntibody-mediated rejection (ABMR) is conventionally defined by the presence of donor-specific anti-human leukocyte antigen (HLA) antibodies (DSA), characteristic microvascular injury on allograft biopsy, and evidence of complement activation, most commonly reflected by C4d deposition. We report the case of a 46-year-old woman who underwent a fully HLA-
Kashiv, Pranjal +3 more
openaire +4 more sources
Impact of Donor-Specific anti-HLA antibodies and donor KIR characteristics in haploidentical HSCT for beta-Thalassemia [PDF]
Mediterranean Journal of Hematology and Infectious Diseases, 2017 In the present study we investigated the role of donor specific HLA antibodies (DSA) and donor KIR repertoire characteristics in a group of 18 patients affected by haemoglobinopathies who underwent haploidentical T cell depleted transplantation.
Marco Andreani +9 more
doaj +2 more sources
Successful treatment of refractory donor‐specific‐human leukocyte antigen‐antibody‐induced primary graft‐failure with daratumumab: A case report [PDF]
eJHaemDonor‐specific anti‐human leukocyte antigen (HLA) antibodies represent a main cause of primary graft failure specifically in the setting of haploidentical stem cell transplantation.
Vadim Lesan +8 more
doaj +3 more sources