Results 21 to 30 of about 8,564,356 (290)

Impact of Transient and Persistent Donor-Specific Antibodies in Lung Transplantation [PDF]

Transplant International
Lung transplantation (LuTx) is an established treatment for patients with end-stage lung diseases, however, outcomes are limited by acute and chronic rejection.
S. Auner, C. Hillebrand, P. M. Boehm, J. Boecker, D. Koren, S. Schwarz, Z. Kovacs, G. Murakoezy, G. Fischer, C. Aigner, K. Hoetzenecker, P. Jaksch, A. Benazzo   +12 more
doaj   +2 more sources

Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies [PDF]

, 2021
Background: Donor-specific antibodies (DSA) against donor human leukocyte antigen after liver transplantation, which are associated with histological changes, have been widely studied with respect to their sustained impact on transplant function. However,
Öllinger, Robert, Eurich, Dennis, Dziodzio, Tomasz, Horst, David, Tacke, Frank, Pratschke, Johann, Maier, Patrick, Sauer, Igor Maximilian, Röhle, Robert, Gül-Klein, Safak, Schmelzle, Moritz, Schöning, Wenzel, Hegermann, Henriette, Plewe, Julius, Lachmann, Nils   +14 more
core   +1 more source

Detection of donor-specific antibodies in kidney transplantation [PDF]

British Medical Bulletin, 2014
Precise and timely detection of human leukocyte antigen (HLA) donor-specific antibodies (DSAs) is vital for evaluating humoral immune status of patients pre- and post-transplantation.Clinically relevant articles on theory, development, methodology and application of HLA-DSA testing in kidney transplantation.The availability of solid phase HLA-antibody ...
Kelley M K, Haarberg, Anat R, Tambur
openaire   +2 more sources

Early Posttransplant Blood Transfusion and Risk for Worse Graft Outcomes

Kidney International Reports, 2021
Introduction: Blood transfusion is a risk factor for allosensitization. Nevertheless, blood transfusion posttransplant remains a common practice. We evaluated the effect of posttransplant blood transfusion on graft outcomes.
Reem Daloul, Juarez R. Braga, Alejandro Diez, April Logan, Todd Pesavento   +4 more
doaj   +1 more source

Early Antibody-Mediated Kidney Transplant Rejection: A Successful Case Without Donor-Specific Anti-HLA Antibodies

Revista Portuguesa de Nefrologia e Hipertensão, 2023
The diagnosis of antibody-mediated rejection has become more common and represents a major cause of kidney graft loss. The ideal treatment remains unknown, with little evidence supporting the use of a specific therapy.
Rita M. Silva, Rita Leal, Maria G. Marques, Luís Rodrigues, Lídia Santos, Catarina Romãozinho, Arnaldo Figueiredo, Rui Alves   +7 more
doaj   +1 more source

Impact of donor-specific anti-HLA antibodies on graft failure and survival after reduced intensity conditioning-unrelated cord blood transplantation: a Eurocord, Société Francophone d’Histocompatibilité et d’Immunogénétique (SFHI) and Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC) analysis

Haematologica, 2013
Graft failure is a major complication after unrelated cord blood transplantation. Presence of HLA-antibodies before cord blood transplantation may impact graft failure.
Annalisa Ruggeri, Vanderson Rocha, Emeline Masson, Myriam Labopin, Renato Cunha, Lena Absi, Ali Boudifa, Brigitte Coeffic, Anne Devys, Muriel De Matteis, Valérie Dubois, Daniel Hanau, Françoise Hau, Isabelle Jollet, Dominique Masson, Beatrice Pedron, Pascale Perrier, Christophe Picard, Annie Ramouneau-Pigot, Fernanda Volt, Dominique Charron, Eliane Gluckman, Pascale Loiseau   +22 more
doaj   +1 more source

Intragraft donor-specific antibodies and lung transplantation [PDF]

European Respiratory Journal, 2019
Intragraft DSA can be found in explanted lungs of patients with chronic lung allograft dysfunction in the absence of circulating DSA. New diagnostic approaches to assess for intragraft DSA may add to our diagnostic arsenal in treating AMR.http://bit.ly ...
Jussi M, Tikkanen, Kathryn, Tinckam
openaire   +2 more sources

Snowflake epitope matching correlates with child-specific antibodies during pregnancy and donor-specific antibodies after kidney transplantation

Frontiers in Immunology, 2022
Development of donor-specific human leukocyte antigen (HLA) antibodies (DSA) remains a major risk factor for graft loss following organ transplantation, where DSA are directed towards patches on the three-dimensional structure of the respective organ ...
Matthias Niemann, Yara Strehler, Nils Lachmann, Fabian Halleck, Klemens Budde, Gideon Hönger, Gideon Hönger, Gideon Hönger, Stefan Schaub, Stefan Schaub, Stefan Schaub, Benedict M. Matern, Eric Spierings, Eric Spierings   +13 more
doaj   +1 more source

DONOR-SPECIFIC ANTIBODIES AS A PREDICTOR OF GRAFT REJECTION AFTER LIVER TRANSPLANTATION [PDF]

Biotechnologia Acta
The main reason for graft loss is the rejection of the donor organ, which may occur at different time after transplantation and may be caused by the recipient’s organism reaction against donor’s human leukocyte antigen (HLA) proteins.
A.V. KUKHOL,, N.A. TSOKOLENKO, A.O. MAZANOVA, Y.A. HROHUL   +3 more
doaj   +1 more source

Role of de novo DQ donor-specific antibody in antibody-mediated rejection in renal transplant recipient: A case study

Asian Journal of Transfusion Science, 2019
The human leukocyte antigen (HLA) matching plays an important role in determining the clinical outcome of renal transplantation. The development of donor specific antibodies (DSA) against HLA is associated with antibody mediated allograft tissue injury ...
Mohit Chowdhry, Manthan Patel, Yogita Thakur, Vandana Sharma   +3 more
doaj   +1 more source