Results 211 to 220 of about 835,082 (382)

Characterisation of an unusual nicotinic acetylcholine receptor subtype preferentially sensitive to biogenic amines. [PDF]

open access: yesCommun Biol
Mitchell EL   +6 more
europepmc   +1 more source

Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot

open access: yesAdvanced Science, EarlyView.
In this study, an “all‐in‐one” engineered anaerobic bacterial system (PDAEcN/COS) is developed for the treatment of immunologically “cold” TNBC. This nanoplatform is capable of colonizing tumor cell surfaces and implementing “self‐blocking” of immune checkpoints, while simultaneously suppressing tumor cells' “don't eat me” signals and delivering “eat ...
Xuanxiang Zhai   +6 more
wiley   +1 more source

A Programmable, 3D Neuron‐On‐Chip Platform Integrating Near Real‐Time Biosensing and Multiaxial Loading for Mechanobiological Injury Profiling

open access: yesAdvanced Science, EarlyView.
A programmable 3D Neuron‐Injury‐on‐a‐Chip platform integrates multiaxial mechanical loading with ultrasensitive electrochemical biosensing to decode neuronal responses in real time. By mimicking physiologically relevant extension–torsion forces, the system reveals load‐specific biomarker trajectories (T‐Tau, NFL), gene regulation, and apoptosis.
Sultan Khetani   +12 more
wiley   +1 more source

Cocaine seeking and consumption are oppositely regulated by mesolimbic dopamine in male rats. [PDF]

open access: yesNat Commun
Burgeno LM   +10 more
europepmc   +1 more source

Programmable Hydrogels: Frontiers in Dynamic Closed‐Loop Systems, Biomimetic Synergy, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
This review summarizes the design principles and key features of programmable hydrogels that respond to multiple stimuli. It then delves into the cutting‐edge mechanisms of self‐executing systems, highlighting their role as the cornerstone of next‐generation programmable hydrogels (NGPHs).
Guangli Xiang   +8 more
wiley   +1 more source

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