Results 1 to 10 of about 3,949,650 (302)
Dopamine agents for hepatic encephalopathy. [PDF]
Cochrane Database Syst Rev, 2014 Patients with hepatic encephalopathy may present with extrapyramidal symptoms and changes in basal ganglia. These changes are similar to those seen in patients with Parkinson's disease. Dopamine agents (such as bromocriptine and levodopa, used for patients with Parkinson's disease) have therefore been assessed as a potential treatment for patients with
Junker AE +3 more
europepmc +5 more sources
"Dopamine homeostasis" requires balanced polypharmacy: Issue with destructive, powerful dopamine agents to combat America's drug epidemic. [PDF]
J Syst Integr Neurosci, 2017 The well-researched pro-dopamine regulator KB220 and variants result in increased functional connectivity in both animal and human brains, and prolonged neuroplasticity (brain cell repair) having been observed in rodents. Moreover, in addition to increased functional connectivity, recent studies show that KB220Z increases overall brain connectivity ...
Blum K +12 more
europepmc +5 more sources
Dopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia
Frontiers in Pharmacology, 2020 Dopamine receptors are widely distributed within the brain where they play critical modulator roles on motor functions, motivation and drive, as well as cognition.
Jean Claude Martel +1 more
doaj +2 more sources
Dopamine receptor antagonists as potential therapeutic agents for ADPKD.
PLoS ONE, 2019 Autosomal dominant polycystic kidney disease (ADPKD) is caused mostly by mutations in polycystin-1 or polycystin-2. Fluid flow leads to polycystin-dependent calcium influx and nuclear export of histone deacetylase 5 (HDAC5), which facilitates the ...
Parama Paul +5 more
doaj +3 more sources
Dual dopamine/serotonin releasers: Potential treatment agents for stimulant addiction. [PDF]
Experimental and Clinical Psychopharmacology, 2008 "Agonist therapy" for cocaine and methamphetamine addiction involves administration of stimulant-like medications (e.g., monoamine releasers) to reduce withdrawal symptoms and prevent relapse. A significant problem with this strategy is that many candidate medications possess abuse liability because of activation of mesolimbic dopamine (DA) neurons in ...
Richard B, Rothman +2 more
openaire +3 more sources
Organothiophosphate Induced Acute and Reversible Parkinsonism: Case Report and Literature Review [PDF]
Asia Pacific Journal of Medical Toxicology, 2021 Introduction: Organophosphate compound poisoning is one of the most common causes for admission to the Medical Intensive Care Unit. Parkinsonism is a primary neurotoxic manifestation of organophosphate intoxication.
PRASHANT THAKUR, C SELVAKUMAR, V Kumar
doaj +1 more source
Future Therapeutic Strategies for Freezing of Gait in Parkinson’s Disease
Frontiers in Human Neuroscience, 2021 Freezing of gait (FOG) is a common and challenging clinical symptom in Parkinson’s disease. In this review, we summarise the recent insights into freezing of gait and highlight the strategies that should be considered to improve future treatment.
Cathy K. Cui, Simon J. G. Lewis
doaj +1 more source
Pharmaceuticals, 2023 We reviewed gastric ulcer healing by dopamine considering several distinctive duodenal key points. Selye and Szabo describe the cysteamine-induced duodenal ulcer in rats as a duodenal stress ulcer in patients.
Predrag Sikiric +24 more
doaj +1 more source
High concentration of dopamine treatment may induce acceleration of human sperm motility
Reproductive Medicine and Biology, 2022 Purpose In humans, catecholamines (including dopamine) have been identified in semen and fallopian tubes, while dopamine D2 receptors (D2DR) are found in the sperm midpiece region.
Hiroki Kanno +5 more
doaj +1 more source
Mesolimbic dopamine adapts the rate of learning from action
bioRxiv, 2021 Analysis of data collected from mice learning a trace conditioning paradigm shows that phasic dopamine activity in the brain can regulate direct learning of behavioural policies, and dopamine sets an adaptive learning rate rather than an error-like ...
Luke T. Coddington, S. Lindo, J. Dudman
semanticscholar +1 more source