Neuroprotection by dopamine agonists [PDF]
, 1994 Research on Parkinson's disease has led to new hypotheses concerning the mechanisms of neurodegeneration and to the development of neuroprotective agents.
Rausch, W. D. +5 more
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Dopamine inactivation efficacy related to functional DAT1 and COMT variants influences motor response evaluation [PDF]
, 2012 BACKGROUND: Dopamine plays an important role in orienting, response anticipation and movement evaluation. Thus, we examined the influence of functional variants related to dopamine inactivation in the dopamine transporter (DAT1) and catechol-O ...
Laucht, Manfred (Prof. Dr.) +31 more
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F1000Research, 2018 Dopamine is a key neurotransmitter, and is widely used as a central nervous system (CNS) agent. Dopamine plays an important role in humans, including a major role in reward and motivation behaviour.
Aman Kundu, Gyanesh Singh
doaj +1 more source
The effects on arterial haemoglobin oxygen saturation and on shunt of increasing cardiac output with dopamine or dobutamine during one-lung ventilation [PDF]
, 2004 Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsTheoretically, if the cardiac output were increased in the presence of a given intrapulmonary shunt, the arterial saturation should improve as the ...
Russell, W., James, M.
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The dopamine hypothesis of drug addiction and its potential therapeutic value.
Frontiers in Psychiatry, 2011 Dopamine (DA) transmission is deeply affected by drugs of abuse, and alterations in DA function are involved in various phases of drug addiction and potentially exploitable therapeutically.
Marco eDiana
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Stimulus representation and the timing of reward-prediction errors in models of the dopamine system [PDF]
, 2008 The phasic firing of dopamine neurons has been theorized to encode a reward-prediction error as formalized by the temporal-difference (TD) algorithm in reinforcement learning.
Sutton, Richard S. +2 more
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Research Progress of PET Molecular Probes Targeting Dopamine D3 Receptor
Journal of Isotopes, 2023 Dopamine D3 receptors are closely related to drug addiction, Parkinson’s disease (PD), schizophrenia and other neuropsychiatric diseases. PET imaging agents that target dopamine D3 receptors can noninvasively show changes in receptor density and status ...
ZHANG Ge, XUE Jingquan, ZHAO Shilun, LIU Yu, YANG Wenjiang
doaj
Propofol Modulates Fear Memory Reconsolidation by Inhibiting D2 Receptor-Expressing Neurons in the Medial Prefrontal Cortex. [PDF]
Adv Sci (Weinh)This study shows that propofol modulates fear‐memory reconsolidation in mice. It works by suppressing D2 receptor‐expressing neurons within the medial prefrontal cortex and their connections to the basolateral amygdala. D2‐receptor agonists reproduce this fear‐reducing effect, offering potential non‐anesthetic therapeutic strategies for trauma‐related ...
Li J +11 more
europepmc +2 more sources
Reinforcement learning or active inference? [PDF]
, 2009 This paper questions the need for reinforcement learning or control theory when optimising behaviour. We show that it is fairly simple to teach an agent complicated and adaptive behaviours using a free-energy formulation of perception.
Friston, K. +17 more
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Prescribing pattern of anti-Parkinson drugs in Japan: a trend analysis from 2005 to 2010.
PLoS ONE, 2014 ObjectiveTherapeutic options for Parkinson's disease mainly consist of L-dopa and dopamine agonists. However, in Japan, the product labeling of the ergot dopamine agonists, cabergoline and pergolide, was revised in April 2007 due to the risk of ...
Sachiko Nakaoka +6 more
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