Results 11 to 20 of about 88,842 (261)

Modafinil as a catecholaminergic agent: empirical evidence and unanswered questions

open access: yesFrontiers in Neurology, 2013
Modafinil, in its two clinical formulations (Provigil® and Nuvigil®), is a widely prescribed wake-promoting therapeutic agent. It binds competitively to the cell membrane dopamine transporter and is dependent on catecholaminergic (dopaminergic ...
Jonathan P Wisor
doaj   +1 more source

Dopamine synergizes with caffeine to increase the heart rate of Daphnia [version 1; referees: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2018
Dopamine is a key neurotransmitter, and is widely used as a central nervous system (CNS) agent.  Dopamine plays an important role in humans, including a major role in reward and motivation behaviour.
Aman Kundu, Gyanesh Singh
doaj   +1 more source

The dopamine hypothesis of drug addiction and its potential therapeutic value.

open access: yesFrontiers in Psychiatry, 2011
Dopamine (DA) transmission is deeply affected by drugs of abuse, and alterations in DA function are involved in various phases of drug addiction and potentially exploitable therapeutically.
Marco eDiana
doaj   +1 more source

Research Progress of PET Molecular Probes Targeting Dopamine D3 Receptor

open access: yesJournal of Isotopes, 2023
Dopamine D3 receptors are closely related to drug addiction, Parkinson’s disease (PD), schizophrenia and other neuropsychiatric diseases. PET imaging agents that target dopamine D3 receptors can noninvasively show changes in receptor density and status ...
ZHANG Ge, XUE Jingquan, ZHAO Shilun, LIU Yu, YANG Wenjiang
doaj  

Prescribing pattern of anti-Parkinson drugs in Japan: a trend analysis from 2005 to 2010.

open access: yesPLoS ONE, 2014
ObjectiveTherapeutic options for Parkinson's disease mainly consist of L-dopa and dopamine agonists. However, in Japan, the product labeling of the ergot dopamine agonists, cabergoline and pergolide, was revised in April 2007 due to the risk of ...
Sachiko Nakaoka   +6 more
doaj   +1 more source

Dopamine’s secret agent: serotonin

open access: yesTrends in Neurosciences
Dopamine suppresses GABA release from striatal terminals in the substantia nigra pars reticulata. Molinari et al. recently demonstrated that this suppression is frequency-dependent-instituting a high-pass filter on striatal 'direct pathway' transmission-and does not require dopamine receptors.
Andrew J. Miller-Hansen, Talia N. Lerner
openaire   +3 more sources

New generation antipsychotics in the treatment of schizophrenia: dopamine stabilizing agents and aripiprazole

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Schizophrenia is a major mental disorder starting mostly during adolescence and cause significant disability. Positive and negative symptoms and cognitive dysfunctions are main domains of schizophrenia. Dopaminergic hyperactivation in mesolimbic regions
Köksal Alptekin
doaj  

Comparison of Dopamine and Norepinephrine Use for the Treatment of Hypotension in Out-Of-Hospital Cardiac Arrest Patients with Return of Spontaneous Circulation

open access: yesEmergency Medicine International, 2020
In patients experiencing out-of-hospital cardiac arrest (OHCA), hypotension is common after return of spontaneous circulation (ROSC). Both dopamine and norepinephrine are recommended as inotropic therapeutic agents.
Chao-Jui Li   +5 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

open access: yesAdvanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim   +6 more
wiley   +1 more source

Dorsal Striatum Dopamine Levels Fluctuate Across the Sleep–Wake Cycle and Respond to Salient Stimuli in Mice

open access: yesFrontiers in Neuroscience, 2019
Dopamine is involved in numerous neurological processes, and its deficiency has been implicated in Parkinson’s disease, whose patients suffer from severe sleep disorders.
Hui Dong   +6 more
doaj   +1 more source

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