Results 1 to 10 of about 1,754,831 (304)

Dopamine agents for hepatic encephalopathy. [PDF]

open access: yesCochrane Database Syst Rev, 2014
Patients with hepatic encephalopathy may present with extrapyramidal symptoms and changes in basal ganglia. These changes are similar to those seen in patients with Parkinson's disease. Dopamine agents (such as bromocriptine and levodopa, used for patients with Parkinson's disease) have therefore been assessed as a potential treatment for patients with
Junker AE   +3 more
europepmc   +5 more sources

Dopamine receptor antagonists as potential therapeutic agents for ADPKD.

open access: yesPLoS ONE, 2019
Autosomal dominant polycystic kidney disease (ADPKD) is caused mostly by mutations in polycystin-1 or polycystin-2. Fluid flow leads to polycystin-dependent calcium influx and nuclear export of histone deacetylase 5 (HDAC5), which facilitates the ...
Parama Paul   +5 more
doaj   +3 more sources

Organothiophosphate Induced Acute and Reversible Parkinsonism: Case Report and Literature Review [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2021
Introduction: Organophosphate compound poisoning is one of the most common causes for admission to the Medical Intensive Care Unit. Parkinsonism is a primary neurotoxic manifestation of organophosphate intoxication.
PRASHANT THAKUR, C SELVAKUMAR, V Kumar
doaj   +1 more source

Future Therapeutic Strategies for Freezing of Gait in Parkinson’s Disease

open access: yesFrontiers in Human Neuroscience, 2021
Freezing of gait (FOG) is a common and challenging clinical symptom in Parkinson’s disease. In this review, we summarise the recent insights into freezing of gait and highlight the strategies that should be considered to improve future treatment.
Cathy K. Cui, Simon J. G. Lewis
doaj   +1 more source

From Selye’s and Szabo’s Cysteamine-Duodenal Ulcer in Rats to Dopamine in the Stomach: Therapy Significance and Possibilities

open access: yesPharmaceuticals, 2023
We reviewed gastric ulcer healing by dopamine considering several distinctive duodenal key points. Selye and Szabo describe the cysteamine-induced duodenal ulcer in rats as a duodenal stress ulcer in patients.
Predrag Sikiric   +24 more
doaj   +1 more source

High concentration of dopamine treatment may induce acceleration of human sperm motility

open access: yesReproductive Medicine and Biology, 2022
Purpose In humans, catecholamines (including dopamine) have been identified in semen and fallopian tubes, while dopamine D2 receptors (D2DR) are found in the sperm midpiece region.
Hiroki Kanno   +5 more
doaj   +1 more source

Restless Legs Syndrome Among the Elderly

open access: yesInternational Journal of Gerontology, 2009
Restless legs syndrome is a sleep and movement disorder that affects 5–15% of the general population, with an increased prevalence among the elderly population.
Pei-Hao Chen, Shih-Jung Cheng
doaj   +1 more source

Dopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia

open access: yesFrontiers in Pharmacology, 2020
Dopamine receptors are widely distributed within the brain where they play critical modulator roles on motor functions, motivation and drive, as well as cognition.
Jean Claude Martel   +1 more
doaj   +1 more source

Dopamine Dynamics and Neurobiology of Non-Response to Antipsychotics, Relevance for Treatment Resistant Schizophrenia: A Systematic Review and Critical Appraisal

open access: yesBiomedicines, 2023
Treatment resistant schizophrenia (TRS) is characterized by a lack of, or suboptimal response to, antipsychotic agents. The biological underpinnings of this clinical condition are still scarcely understood.
Felice Iasevoli   +8 more
doaj   +1 more source

Modafinil as a catecholaminergic agent: empirical evidence and unanswered questions

open access: yesFrontiers in Neurology, 2013
Modafinil, in its two clinical formulations (Provigil® and Nuvigil®), is a widely prescribed wake-promoting therapeutic agent. It binds competitively to the cell membrane dopamine transporter and is dependent on catecholaminergic (dopaminergic ...
Jonathan P Wisor
doaj   +1 more source

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