Results 191 to 200 of about 1,754,831 (304)

Polydopamine-Based Biomaterials in Oral Medicine: Applications, Mechanisms, and Translational Challenges. [PDF]

Int J Nanomedicine
Yang Z, Song W, Lv L, Zhai S, Liu Y, Cui H, Li X, Gao F, Chu S.   +8 more
europepmc   +1 more source

Orthostatic Myoclonus—Clinical and Electrophysiological Features in a Large Retrospective Cohort

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Orthostatic myoclonus is characterized by irregular, lower limb myoclonic bursts during stance and is a major cause of postural instability and falls. However, studies are limited, and little is known about its pathophysiology. Objectives We sought to define the clinical and electrophysiological features of orthostatic myoclonus in ...
Sai A. Nagaratnam, Niroshan Jeyakumar, Gobishan Jeyakumar, Florence Chang, Duncan Wilson, Paloma Becker, Hugo Morales‐Briceno, Neil Mahant, Victor S.C. Fung   +8 more
wiley   +1 more source

Disease‐Duration–Specific Percentiles for Prospective Subtyping of Parkinson's Disease: A PPMI‐Based Study

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is clinically heterogeneous, with variable progression rates that complicate clinical trial design. The data‐driven diffuse malignant (DM), intermediate (IM), and mild‐motor predominant (MMP) subtyping model has prognostic value but lacks disease duration–specific thresholds for prospective use in disease ...
Ahmed Negida, Nitai Mukhopadhyay, Brian D. Berman, Seyed‐Mohammad Fereshtehnejad, Matthew J. Barrett   +4 more
wiley   +1 more source

Secondary parkinsonism associated with tetrabenazine: A case report. [PDF]

Dusunen Adam
Simar AS, Samanci MY, Zirh A, Yilmaz NH.
europepmc   +1 more source

Machine Learning Prediction of Hoehn and Yahr Scores at 5‐Years Post‐123I‐Ioflupane SPECT Imaging in a Real‐World Parkinson's Disease Dataset

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) progression is highly heterogeneous, complicating clinical management and prognostication. While machine learning models have been developed using research datasets such as Parkinson's Precision Medicine Initiative (PPMI) and Parkinson's Disease Biomarkers Program (PDBP), their clinical translatability is ...
Xuehua Ye, Mette Niemann Johansen, Balazs Laczi, Mads Peter Horndrup, Michael Zaucha Sørensen, Rasmus Vestergård Madsen, Jan Wolber, Markus Lonsdale, Annemette Lokkegaard, Renee Miller   +9 more
wiley   +1 more source

Moringa oleifera Lam. Seed Lectin (WSMoL) Attenuates Parkinsonian Symptoms in Mice via Anti-Inflammatory, Antioxidant, and Neurotransmitter-Modulating Effects. [PDF]

Chem Biodivers
Patriota LLS, Leão EDLM, da Silva MNB, Marinho AO, de Lima BRF, da Costa JA, de Amorim LC, Santos VBS, Paiva PMG, Pereira MC, Napoleão DC, Cavalcanti JVFL, Vieira LD, da Rosa MM, Napoleão TH.   +14 more
europepmc   +1 more source

Engineering Nanocarriers for Dopamine Stabilization and Targeted Brain Delivery: Mechanisms, Approaches and Translational Challenges. [PDF]

Int J Nanomedicine
Patra S, Nathani A.
europepmc   +1 more source

COVID‐19 Amplifies Sex‐Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model

Movement Disorders, EarlyView.
Abstract Background Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID‐19 remains uncertain. Objectives We investigated the plausible link between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and
Ifeoluwa Awogbindin, Mélanie Bourque, Marc Morissette, Marie‐Ève Hamelin, Chantal Rhéaume, Jared VanderZwaag, Antonia Landwehr, Disha Patel, Guy Boivin, Marie‐Ève Tremblay, Thérèse Di Paolo   +10 more
wiley   +1 more source

The Effect of Dopaminergic Medication on Impulse Control and Compulsive Behaviour: A Translational Perspective. [PDF]

Basic Clin Pharmacol Toxicol
Wolfschlag M, Espa E, Hauer KO, Timpka J, Smith R, Odin P, Cenci MA, Håkansson A.   +7 more
europepmc   +1 more source

Association Between Long‐Term Exposure to Air Pollution and Parkinson's Disease: Administrative Cohort of Older Adults in South Korea

Movement Disorders, EarlyView.
Abstract Background Evidence regarding the association between long‐term exposure to ambient air pollution and Parkinson's disease (PD) remains inconsistent, particularly among older adults in Asian populations. Objective We aimed to examine the association between long‐term exposure to ambient air pollutants and incident PD in a nationwide ...
Jongmin Oh, Jisun Myung, Dong‐Wook Lee, Changwoo Han, Yun‐Chul Hong, Soontae Kim, Yoon‐Hee Kang, Hyun‐Joo Bae, Youn‐Hee Lim   +8 more
wiley   +1 more source