Results 221 to 230 of about 3,949,650 (302)
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Agents acting on central dopamine receptors

1977
Dopamine was long believed to be only of functional significance as a precursor of epinephrine and norepinephrine. It became a focus of interest only after Carlsson’s [1] demonstration of its presence in relatively high concentrations in various parts of the brain, mainly striatum [2] and inner retina [3].
N, Kumar, P C, Jain
openaire   +2 more sources

Tardive Syndromes are Rarely Reversible after Discontinuing Dopamine Receptor Blocking Agents: Experience from a University-based Movement Disorder Clinic

Tremor and Other Hyperkinetic Movements, 2014
Background Several studies have examined reversibility of tardive syndromes (TS), primarily in psychotic patients who are maintained on dopamine receptor blocking drugs. The results have varied widely.
Deepti Zutshi, L. Cloud, S. Factor
semanticscholar   +1 more source

A comprehensive review of monoamine oxidase inhibitors as Anti-Alzheimer's disease agents: A review.

European journal of medicinal chemistry, 2020
Monoamine oxidases (MAO-A and MAO-B) are mammalian flavoenzyme, which catalyze the oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine, serotonin, and some other amines.
Shoaib Manzoor, Nasimul Hoda
semanticscholar   +1 more source

Movement Disorders Induced by Dopamine Blocking Agents

Seminars in Neurology, 2001
Movement disorders are frequently due to dopamine blocking agents (DBAs) prescribed for psychiatric illnesses. DBAs are sometimes also prescribed inappropriately for other maladies. These drugs can cause a wide variety of involuntary movements, sometimes in combination.
openaire   +2 more sources

Chapter 2 Antipsychotic Agents and Dopamine Agonists

1978
Publisher Summary This chapter summarizes the effective results of neuroleptic (antipsychotic) drugs in symptomatic treatment of schizophrenia, whose etiologies are unknown and may not be identical. This review begins with the recent discoveries about dopamine (DA) receptors.
John McDermed, Richard J. Miller
openaire   +1 more source

ENDOCRINE EFFECTS OF DOMPERIDONE: A PERIPHERAL DOPAMINE BLOCKING AGENT

Clinical Endocrinology, 1981
SUMMARYIn the present study, effects of domperidone, a peripheral dopamine blocking agent, on prolactin and growth hormone were examined to determine whether dopamine regulation of these hormones involved structures external to the blood‐brain barrier. A clearcut elevation in prolactin was produced by domperidone.
G M, Brown   +3 more
openaire   +2 more sources

The role of dopamine in mood disorders and the associated changes in circadian rhythms and sleep-wake cycle.

Brain Research, 2019
Dopamine is primarily produced in the substantia nigra (SN) and the ventral tegmentum area (VTA) in the brain. It plays a well-established role in the motor control, reward, mood regulation and addiction behaviour.
Basma Radwan, He Liu, D. Chaudhury
semanticscholar   +1 more source

Inhibition of dopamine β-hydroxylase by bidentate chelating agents

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1990
1-2H-Phthalazine hydrazone (hydralazine; HYD), 2-1H-pyridinone hydrazone (2-hydrazinopyridine; HP), 2-quinoline-carboxylic acid (QCA), 1-isoquinolinecarboxylic acid (IQCA), 2,2'-bi-1H-imidazole (2,2'-biimidazole; BI), and 1H-imidazole-4-acetic acid (imidazole-4-acetic acid; IAA) directly and reversibly inhibit homogeneous soluble bovine dopamine beta ...
S, Townes, C, Titone, R C, Rosenberg
openaire   +2 more sources

Presynaptic regulation of dopamine release: Role of the DAT and VMAT2 transporters

Neurochemistry International, 2019
&NA; The signaling dynamics of the neurotransmitter dopamine has been established to have an important role in a variety of behavioural processes including motor control, cognition, and emotional processing.
Kevin G. Mulvihill
semanticscholar   +1 more source

Tc-99m-Labeled Tropanes as Dopamine Transporter Imaging Agents

Bioconjugate Chemistry, 1996
The development of novel Tc-9m-labeled tropane derivatives as dopamine transporter imaging agents is reported. A series of neutral and lipophilic conjugated complexes, containing N-(alkylthiolato)-tropane, aminobis(ethylthiolato), and a [99mTc]TcO3+ center core, were prepared and evaluated as central nervous system (CNS) dopamine transporter imaging ...
S, Meegalla   +6 more
openaire   +2 more sources

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