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IV inotropic agents: dopamine, dobutamine, and amrinone
Critical Care Nurse, 1990Three commonly used IV inotropic agents--dopamine, dobutamine, and amrinone--have been discussed in this article. Knowledge of their common mechanisms of action, individual actions, dosages, methods of preparation, precautions, and side effects can only help critical care nurses maintain or improve the quality of care given to patients receiving these ...
J, Budny, K, Anderson-Drevs
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Dopamine D3 receptor antagonists as therapeutic agents
Drug Discovery Today, 2005The behavioral and pathophysiological role of the dopamine D(3) receptor, which was deduced from anatomical, lesion and drug treatment studies in the ten years following cloning of the receptor, indicated that its functions differed from those of the D(2) receptor.
Jeffrey N, Joyce, Mark J, Millan
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Dopamine D2 receptor agents, but not dopamine D1, modify brain glucose metabolism
Brain Research, 1985The effects of recently described selective dopamine D1 and D2 agonists and antagonists on brain glucose metabolism were studied using the 2-[14C]deoxyglucose autoradiographic technique. The administration of LY-141865 or YM-09151-2, which behave as a specific D2 agonist and antagonist respectively, modified brain glucose metabolism in a manner similar
J M, Palacios, K H, Wiederhold
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Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT
Journal of Medicinal Chemistry, 1993A novel series of dual-labeling D2 dopamine agents (labeled with either 18F or 123I for PET or SPECT imaging, respectively) was investigated. Two desired fluorinated and iodinated dopamine agents, FIDA1, (S)-(-)-2-(2-fluoroethoxy)-5-iodo-3-methoxy-N-[(1-ethyl-2- pyrrolidinyl)methyl]-benzamide, and FIDA2, (R)-(+)-2,3-dimethoxy-5-iodo-N-[(1-(4 ...
S, Chumpradit +4 more
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Agents acting on central dopamine receptors
1977Dopamine was long believed to be only of functional significance as a precursor of epinephrine and norepinephrine. It became a focus of interest only after Carlsson’s [1] demonstration of its presence in relatively high concentrations in various parts of the brain, mainly striatum [2] and inner retina [3].
N, Kumar, P C, Jain
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Chapter 2 Antipsychotic Agents and Dopamine Agonists
1978Publisher Summary This chapter summarizes the effective results of neuroleptic (antipsychotic) drugs in symptomatic treatment of schizophrenia, whose etiologies are unknown and may not be identical. This review begins with the recent discoveries about dopamine (DA) receptors.
John McDermed, Richard J. Miller
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A role for dopamine in feeding responses produced by orexigenic agents
Brain Research, 2004Dopamine-deficient (DD) mice become hypophagic and die of starvation by 3 to 4 weeks of age unless dopamine is restored by daily treatment with l-3-4-dihydroxyphenylalanine (l-dopa). We demonstrate here that DD mice mount qualitatively normal counter-regulatory blood glucose responses to insulin and 2-deoxy-d-glucose (2-DG).
Thomas S, Hnasko +4 more
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Movement Disorders Induced by Dopamine Blocking Agents
Seminars in Neurology, 2001Movement disorders are frequently due to dopamine blocking agents (DBAs) prescribed for psychiatric illnesses. DBAs are sometimes also prescribed inappropriately for other maladies. These drugs can cause a wide variety of involuntary movements, sometimes in combination.
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The Role of Dopaminergic Agents and the Dopamine Receptor in Treatment for CHF
The Journal of Clinical Pharmacology, 1989Cet article etudie l'opportunite de l'utilisation des substances dopaminergiques dans le traitement de l'insuffisance cardiaque congestive comme alternative au traitement par digitaliques et diuretiques. Les proprietes cardiovasculaires de la dopamine, la propylbutyldopamine, le levodopa et la dobutamine sont connues et ces substances presentent ...
R A, Carey, L, Jacob
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