Results 251 to 260 of about 1,754,831 (304)
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ENDOCRINE EFFECTS OF DOMPERIDONE: A PERIPHERAL DOPAMINE BLOCKING AGENT
Clinical Endocrinology, 1981SUMMARYIn the present study, effects of domperidone, a peripheral dopamine blocking agent, on prolactin and growth hormone were examined to determine whether dopamine regulation of these hormones involved structures external to the blood‐brain barrier. A clearcut elevation in prolactin was produced by domperidone.
G M, Brown +3 more
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Update on the Pharmacological Treatment of Tics with Dopamine-Modulating Agents
ACS Chemical Neuroscience, 2018More than 40 years of research and clinical practice have proven the effectiveness of dopamine receptor antagonists in the pharmacological treatment of tics. A blockade of the striatal dopamine-D2 receptors is mainly responsible for their tic-reducing effect.
Sabine Mogwitz +3 more
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Inhibition of dopamine β-hydroxylase by bidentate chelating agents
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 19901-2H-Phthalazine hydrazone (hydralazine; HYD), 2-1H-pyridinone hydrazone (2-hydrazinopyridine; HP), 2-quinoline-carboxylic acid (QCA), 1-isoquinolinecarboxylic acid (IQCA), 2,2'-bi-1H-imidazole (2,2'-biimidazole; BI), and 1H-imidazole-4-acetic acid (imidazole-4-acetic acid; IAA) directly and reversibly inhibit homogeneous soluble bovine dopamine beta ...
S, Townes, C, Titone, R C, Rosenberg
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Effects of alkylating agents on dopamine D3 receptors in rat brain: selective protection by dopamine
Brain Research, 1999Dopamine D(3) receptors are structurally highly homologous to other D(2)-like dopamine receptors, but differ from them pharmacologically. D(3) receptors are notably resistant to alkylation by 1-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ), which readily alkylates D(2) receptors. We compared EEDQ with N-(p-isothiocyanatophenethyl)spiperone (NIPS),
K, Zhang +4 more
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Characteristics of Inpatients Prescribed Dopamine Receptor Blocking Agents
Psychopharmacology BulletinDopamine receptor blocking agents (DRBAs, also known as antipsychotics) are frequently used in hospitalized patients. These medications carry a significant side effect burden and should be used judiciously. This purpose of this study is to examine patient, disease, and medication characteristics associated with the use of DRBAs in the inpatient setting
Shaina, Schwartz +4 more
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Clinical Pharmacology of Dopamine-Modulating Agents in Tourette’s Syndrome
2013Forty years of research and clinical practice have proved dopamine (DA) receptor antagonists to be effective agents in the treatment of Tourette's syndrome (TS), allowing a significant tic reduction of about 70%. Their main effect seems to be mediated by the blockade of the striatal DA-D2 receptors. Various typical and atypical agents are available and
Sabine, Mogwitz +3 more
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Chapter 2. Antipsychotic Agents and Dopamine Agonists
1980Publisher Summary With respect to the DA theory of schizophrenia, arguments have recently been presented that increased dopaminergic transmission produces positive symptomatology of schizophrenia (Type I syndrome, equivalent to an acute state of the disease), while other factors, such as structural changes in the brain, produce the negative ...
David C. Remy, Gregory E. Martin
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Inhibition of ribonucleotide reductase by antitumor agents related to levodopa and dopamine
Biochemical Pharmacology, 1985Using partially purified enzyme from L1210 cells, dihydroxybenzene derivatives related structurally to dopamine were shown to reversibly inactivate ribonucleotide reductase. A structure-activity analysis revealed that derivatives with side-chains, which contain a negatively-charged group, had significantly reduced inhibitory activity.
G B, FitzGerald, M M, Wick
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Vestibular compensation is affected by treatment with dopamine active agents.
Archives italiennes de biologie, 1993The aim of the present work was to examine the effects of postoperative treatments with agents active on dopaminergic system on vestibular recovery from the postural and ocular symptoms which follow a unilateral labyrinthectomy. Hemilabyrinthectomized guinea pigs were given a daily i.p.
PETROSINI, Laura, M. E. Dell'Anna
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Chapter 5. Dopamine Receptors and Dopaminergic Agents
1985Publisher Summary This chapter discusses the recent developments in the field of dopamine (DA) receptors and dopaminergic agents. Classification of DA receptors has been simplified considerably. Earlier receptor binding studies had indicated the existence of four distinct receptor subtypes, identified as D-1, D-2, D-3, and D-4. Evidence now indicates
John M. Schaus, James A. Clemens
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