Results 41 to 50 of about 3,949,650 (302)

Dopamine differentiation factors produce partial motor recovery in 6-hydroxydopamine lesioned rats

Neurobiology of Disease, 1995
Two-week infusion of muscle-derived differentiation factor (MDF), or human recombinant acidic fibroblast growth factor (aFGF) and/or its muscle-derived activating substance into the striatum of unilaterally 6-hydroxydopamine (6-OHDA)-lesioned rats caused
B.K. Jin, L. Iacovitti
doaj   +1 more source

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

Multi‐Scale Interface Engineering of MXenes for Multifunctional Sensory Systems

Advanced Functional Materials, EarlyView.
MXenes, as two‐dimensional transition metal carbides and nitrides, demonstrate remarkable capabilities for multifunctional sensing applications. This review systematically examines multi‐scale interface engineering approaches that enhance sensing performance, enable diverse detection functionalities, and improve system‐level compatibility in MXene ...
Jiaying Liao, Sin‐Yi Pang, Jianhua Hao
wiley   +1 more source

Dopamine Modulates Adaptive Prediction Error Coding in the Human Midbrain and Striatum

Journal of Neuroscience, 2017
Learning to optimally predict rewards requires agents to account for fluctuations in reward value. Recent work suggests that individuals can efficiently learn about variable rewards through adaptation of the learning rate, and coding of prediction errors
K. Diederen, H. Ziauddeen, M. Vestergaard, T. Spencer, W. Schultz, P. Fletcher   +5 more
semanticscholar   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Efficacy of dopamine antagonists in stimulating ovulation and spermiation of Caspian kutum (Rutilus frisii) under controlled conditions

Journal of the World Aquaculture Society
The present study compared the effectiveness of dopamine antagonists and commercial hormonal agents containing GnRH analogs combined with dopamine antagonists for inducing ovulation and spermiation in Caspian kutum (Rutilus frisii) spawners.
Erfan Akbari Nargesi, Dariusz Kucharczyk, Danial Gorouhi, Joanna Nowosad, Behrooz Heidari   +4 more
doaj   +1 more source

Neuroleptic malignant syndrome in an adolescent with the GNAO1 mutation movement disorder phenotype: a challenging diagnosis

Portuguese Journal of Pediatrics
Introduction: Neuroleptic malignant syndrome (NMS) is a rare and life-threatening condition resulting from exposure to dopamine-blocking agents. GNAO1 mutations are a neurodevelopmental disorder associated with a hyperkinetic movement disorder, usually ...
Mónica Santos, Tiago Proença dos Santos, Sofia Almeida, Miguel Coelho, António Levy   +4 more
doaj   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Activation of the dopamine 1 and dopamine 5 receptors increase skeletal muscle mass and force production under non-atrophying and atrophying conditions

BMC Musculoskeletal Disorders, 2011
Background Control of skeletal muscle mass and force production is a complex physiological process involving numerous regulatory systems. Agents that increase skeletal muscle cAMP levels have been shown to modulate skeletal muscle mass and force ...
Dietrich Jeffrey A, Dolan Elizabeth T, Lefever Frank R, Hinkle Richard T, Reichart Deborah L, Sibley David R, Isfort Robert J   +6 more
doaj   +1 more source