Normal spatial learning and improved spatial working memory in mice (mus musculus) lacking dopamine d4 receptors [PDF]
Dopamine terminals in the hippocampus and prefrontal cortex modulate cognitive processes such as spatial learning and working memory. Because dopamine D4 receptors are expressed in these brain areas we have analyzed mutant mice lacking this receptor ...
Avale, Maria Elena +3 more
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Small cell lung cancer (SCLC) is difficult to treat due to its aggressiveness, early metastasis, and rapid development of resistance to chemotherapeutic agents.
Sk. Kayum Alam +10 more
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The neuroleptic-like peptide desenkephalin-γ-endorphin does not antagonize the dopamine receptor agonist-induced inhibition of the release of [3H]dopamine from rat nucleus accumbens slices in vitro [PDF]
F.S. Radhakishun +4 more
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Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]
Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core
Aripiprazole, an atypical antipsychotic drug, is a D2dopamine–receptor partial agonist, but also has affinity to several serotonin receptors (5-HT1A,2A,2C,7).
Shuntaro Kohnomi +3 more
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: κ-Opioid receptor agonists decrease the levels of extracellular dopamine in vivo and in vitro. However, the mechanism(s) underlying these actions are unclear.
Nuannoi Chudapongse +3 more
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The Effects of Neurosteroids, such as Pregnenolone Sulfate and its receptor, TrpM3 in the Retina. [PDF]
Pregnenolone sulfate (PregS) is the precursor to all steroid hormones and is produced in neurons in an activity dependent manner. Studies have shown that PregS production is upregulated during certain critical periods of development, such as in the first
Webster, Corey Michael
core
Dopamine Has a Critical Role in Photoreceptor Degeneration in the rd Mouse
Photoreceptors receive paracrine input from dopaminergic interplexiform cells. Rod photoreceptors in the rd mouse degenerate rapidly due to a specific gene defect.
Judith Mosinger Ogilvie, Judith D. Speck
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The role of the neuromodulator adenosine in alcohols actions. [PDF]
The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters.
Diamond, Ivan, Dohrman, D, Gordon, A
core
Differential effects of dopamine agonists upon stimulated limbic and striatal dopamine release: in vivo voltammetric data [PDF]
Jonathan A. Stamford +2 more
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