Results 91 to 100 of about 120,942 (241)

Normal spatial learning and improved spatial working memory in mice (mus musculus) lacking dopamine d4 receptors [PDF]

open access: yes, 2001
Dopamine terminals in the hippocampus and prefrontal cortex modulate cognitive processes such as spatial learning and working memory. Because dopamine D4 receptors are expressed in these brain areas we have analyzed mutant mice lacking this receptor ...
Avale, Maria Elena   +3 more
core   +1 more source

Dopamine D2 receptor agonists abrogate neuroendocrine tumour angiogenesis to inhibit chemotherapy-refractory small cell lung cancer progression

open access: yesCell Death and Disease
Small cell lung cancer (SCLC) is difficult to treat due to its aggressiveness, early metastasis, and rapid development of resistance to chemotherapeutic agents.
Sk. Kayum Alam   +10 more
doaj   +1 more source

Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]

open access: yes, 2019
Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core  

Effect of Aripiprazole on 5-HT2Receptor–mediated Wet-Dog Shake Responses and Disruption of Prepulse Inhibition in Rats

open access: yesJournal of Pharmacological Sciences, 2008
Aripiprazole, an atypical antipsychotic drug, is a D2dopamine–receptor partial agonist, but also has affinity to several serotonin receptors (5-HT1A,2A,2C,7).
Shuntaro Kohnomi   +3 more
doaj   +1 more source

Nonspecific Effects of the Selective κ-Opioid Receptor AgonistU-50,488H on Dopamine Uptake and Release in PC12 Cells

open access: yesJournal of Pharmacological Sciences, 2003
: κ-Opioid receptor agonists decrease the levels of extracellular dopamine in vivo and in vitro. However, the mechanism(s) underlying these actions are unclear.
Nuannoi Chudapongse   +3 more
doaj   +1 more source

The Effects of Neurosteroids, such as Pregnenolone Sulfate and its receptor, TrpM3 in the Retina. [PDF]

open access: yes, 2019
Pregnenolone sulfate (PregS) is the precursor to all steroid hormones and is produced in neurons in an activity dependent manner. Studies have shown that PregS production is upregulated during certain critical periods of development, such as in the first
Webster, Corey Michael
core  

Dopamine Has a Critical Role in Photoreceptor Degeneration in the rd Mouse

open access: yesNeurobiology of Disease, 2002
Photoreceptors receive paracrine input from dopaminergic interplexiform cells. Rod photoreceptors in the rd mouse degenerate rapidly due to a specific gene defect.
Judith Mosinger Ogilvie, Judith D. Speck
doaj   +1 more source

The role of the neuromodulator adenosine in alcohols actions. [PDF]

open access: yes, 1997
The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters.
Diamond, Ivan, Dohrman, D, Gordon, A
core  

Home - About - Disclaimer - Privacy