Results 111 to 120 of about 123,913 (326)

The Feasibility and Practical Utility of Virtual Visits for Patients with Parkinson's Disease in Different World Regions

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Overcoming existing access barriers is crucial for better‐specialized health care of patients with Parkinson's disease (PD). Objective The aim of the study was to compare the access and visit quality/acceptability between in‐office and virtual telemedicine visits.
Álvaro García‐Bustillo   +11 more
wiley   +1 more source

Probing the role of the cation–π interaction in the binding sites of GPCRs using unnatural amino acids [PDF]

open access: yes, 2009
We describe a general application of the nonsense suppression methodology for unnatural amino acid incorporation to probe drug–receptor interactions in functional G protein-coupled receptors (GPCRs), evaluating the binding sites of both the M2 muscarinic
Ballesteros   +31 more
core   +3 more sources

Dopamine D2 receptor agonists abrogate neuroendocrine tumour angiogenesis to inhibit chemotherapy-refractory small cell lung cancer progression

open access: yesCell Death and Disease
Small cell lung cancer (SCLC) is difficult to treat due to its aggressiveness, early metastasis, and rapid development of resistance to chemotherapeutic agents.
Sk. Kayum Alam   +10 more
doaj   +1 more source

Comparative Analysis of the Incidence, Prevalence, and Survival of 8 Types of Parkinsonism in a Population‐Based Study with 367 Million Person Years of Observation over 21 Years

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi   +7 more
wiley   +1 more source

The challenge of perioperative pain management in opioid-tolerant patients [PDF]

open access: yes, 2017
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F   +9 more
core   +2 more sources

Clinical Algorithm‐Guided Approach to Botulinum Toxin Type A Treatment for Axial Postural Abnormalities in Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Axial postural abnormalities (APAs) are common, disabling complications of Parkinson's disease (PD) with unclear pathophysiology. The presence of hyperactivity in multiple trunk muscles supports the use of botulinum toxin (BTA). However, its application is complex, due to the lack of standardized clinical and electrophysiological ...
Giacomo Argenziano   +7 more
wiley   +1 more source

Therapeutic challenges of giant invasive cystic macroprolactinoma

open access: yesEndocrinology, Diabetes & Metabolism Case Reports
Giant cystic prolactinomas are extremely rare, with only four cases previously reported in the literature. Herein, we report the case of a 59-year-old male who presented with an acute decline in visual acuity.
S Mekni   +6 more
doaj   +1 more source

Reinforcing properties of Pramipexole in normal and parkinsonian rats

open access: yesNeurobiology of Disease, 2013
Striatal D2 and D3 dopamine receptors are involved in mediating the reinforcing properties of natural rewards and drugs. In Parkinson's disease, while D2/3 dopamine agonists alleviate motor symptoms, behavioral addictions and withdrawal syndrome are ...
Michel Engeln   +5 more
doaj   +1 more source

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