Results 151 to 160 of about 554,589 (315)

Chronic exposure to dopamine agonists affects the integrity of striatal D2 receptors in Parkinson's patients

open access: yesNeuroImage: Clinical, 2017
We aimed to investigate the integrity and clinical relevance of striatal dopamine receptor type-2 (D2R) availability in Parkinson's disease (PD) patients. We studied 68 PD patients, spanning from early to advanced disease stages, and 12 healthy controls.
Marios Politis   +4 more
doaj  

Anosmia and Upper Limb Rigidity—A Potential Phenotype of Idiopathic Normal Pressure Hydrocephalus with Cerebrospinal Fluid α‐Synuclein Seeds

open access: yesMovement Disorders, EarlyView.
Abstract Background The pathophysiology of idiopathic normal pressure hydrocephalus (iNPH) and its association with neurodegenerative disorders is poorly understood. Objectives The aim was to determine the prevalence of α‐synuclein pathology in iNPH and its associations with clinical characteristics. Methods We used α‐synuclein seed amplification assay
Sandrina Weber   +9 more
wiley   +1 more source

Expanding the spectrum of KCNJ6‐related disorders: Milder phenotype with pathological startle responses

open access: yesClinical Genetics, Volume 103, Issue 1, Page 103-108, January 2023., 2023
We describe here the case of a 36‐year‐old female with a de novo pathogenic variant in KCNJ6 (NM_002240.5: c.460G>T; p.(Gly154Cys)) presenting with mild intellectual disability, subtle dysmorphic features, obsessive–compulsive disorder, and an exaggerated startle response, thereby expanding the spectrum of KCNJ6‐related disorders to milder phenotypes ...
Vesna Marija van Midden   +4 more
wiley   +1 more source

No Dopamine Agonist Modulation of Brain [18F]FEOBV Binding in Parkinson's Disease. [PDF]

open access: yesMol Pharm, 2022
Albin RL   +7 more
europepmc   +1 more source

Unsettling the Hegemony of Intention: Agonistic Image Generation [PDF]

open access: yesarXiv
Current image generation paradigms prioritize actualizing user intention - "see what you intend" - but often neglect the sociopolitical dimensions of this process. However, it is increasingly evident that image generation is political, contributing to broader social struggles over visual meaning.
arxiv  

The agonist activities of the putative antipsychotic agents, L‐745,870 and U‐101958 in HEK293 cells expressing the human dopamine D4.4 receptor [PDF]

open access: green, 1998
Lucien Gazi   +9 more
openalex   +1 more source

Cognitive and Psychiatric Adverse Effects of Foslevodopa/Foscarbidopa in Patients with Parkinson's Disease

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Sacha Brohée   +9 more
wiley   +1 more source

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