Results 251 to 260 of about 118,448 (336)

Current Insights Into Individualized Diagnosis and Treatment of Allergic Rhinitis Based on Phenotype and Endotype

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu   +7 more
wiley   +1 more source

Feedback inhibition of dopamine synthesis by continuous administration of dopamine agonists

open access: gold, 2000
Shin-ichi Iwata   +3 more
openalex   +1 more source

An epigenomic threshold hypothesis for integrating dynamic environmental signals into functional models of developmental polyphenisms

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Interactions between developing embryos and a multitude of environmental factors (e.g. climate, nutrition, social cues, stress and anthropogenic contaminants) underlie adaptive and non‐adaptive developmental plasticity and carry broad implications across ecological ...
Benjamin B. Parrott, Samantha L. Bock
wiley   +1 more source

Dihydrexidine — The First Full Dopamine D1 Receptor Agonist [PDF]

open access: green, 2004
Peter Salmi, Ruben Isacson, Björn Kull
openalex   +1 more source

Chronic intermittent alcohol yields sex‐specific disruptions in cortical‐striatal‐limbic oscillations in rats

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
This study shows that chronic alcohol exposure leads to sex‐specific disruptions in local field potentials, specifically causing changes to amygdala oscillations in females and prefrontal cortical and nucleus accumbens oscillations in males. These data may explain some of the sex differences observed in alcohol misuse and provide potential biomarkers ...
Kelly A. Hewitt   +4 more
wiley   +1 more source

Treatment of Early‐Onset Specified and Unspecified Bipolar Disorders: A Systematic Review and Strategies for Identifying and Managing a Thermally Dysregulated Subtype in Children

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Bipolar disorder (BD), characterized by extreme mood shifts between mania and depression, can manifest in childhood, and pose treatment challenges. Treatment for full‐criteria BD I or II in children has been partially described in the literature, but major uncertainties exist regarding non‐classic presentations, which were ...
Demitri F. Papolos   +2 more
wiley   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

open access: yesAddiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper   +7 more
wiley   +1 more source

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