Results 121 to 130 of about 103,481 (331)

Progress of non‐motor symptoms in early‐onset Parkinson's disease

open access: yesIbrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang   +5 more
wiley   +1 more source

Recent applications of magnetic iron oxide nanoparticles for cerebral blood volume quantification in functional magnetic resonance imaging

open access: yesIbrain, EarlyView.
This study explores the recent advances in the use of iron oxide nanoparticles (IONPs) in functional MRI (fMRI) for studying brain functions, specifically cerebral blood volume (CBV) measurements. It covers fMRI techniques, magnetic nanoparticle synthesis, coating methods, and their applications in CBV imaging, in comparison to other contrast agents in
Giorgio Capuzzello   +3 more
wiley   +1 more source

Dopamine Agonist Prescribing in a Gambling Disorder Patient Population: A Clinical Audit to Determine Prevalence in the NHS Northern Gambling Service

open access: yesBJPsych Open
Aims: Dopamine agonists are prescribed to treat several major physical and mental illnesses. Rotigotine, ropinerole, pramipexole (full agonists) are routinely used to treat symptoms of restless leg syndrome, whilst aripiprazole (partial agonist) is used ...
John Barker, Rebecca Lees
doaj   +1 more source

Genetic and Environmental Associations Among Pain, Sleep Disturbances, and Substance Use Intent in Early Adolescence

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Purpose Pain, sleep disturbances, and substance use are common in adolescence, with research indicating that genetic and environmental factors account for variation in each of these behavioral and health outcomes. Moreover, pain, sleep disturbances, and substance use often co‐occur during adolescence. However, research has not examined whether
Kit K. Elam   +4 more
wiley   +1 more source

Prenatal Nicotine Exposure as a Teratogen in Neurological Pathways [PDF]

open access: yes, 2016
Attention-deficit/hyperactivity disorder (ADHD) is the most heritable and commonly diagnosed childhood psychiatric disorder with 4% of all children being diagnosed with this disorder.
Grover, Monica
core   +1 more source

Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U   +6 more
wiley   +1 more source

Long‐Term Safety and Efficacy of Repeat Treatments with DaxibotulinumtoxinA in Cervical Dystonia: Results from the ASPEN‐Open‐Label Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background DaxibotulinumtoxinA (DAXI), a novel botulinum neurotoxin (BoNT) formulation, was shown to be safe, effective, and long‐lasting in the treatment of cervical dystonia (CD) over one treatment cycle in the phase 3, randomized, placebo‐controlled ASPEN‐1 trial.
Peter McAllister   +11 more
wiley   +1 more source

Activation of 5-HT 2A Receptor Disrupts Rat Maternal Behavior [PDF]

open access: yes, 2019
Serotonin 5-HT2A receptor is widely distributed in the central nervous system and plays an important role in sensorimotor function, emotion regulation, motivation, executive control, learning and memory. We investigated its role in rat maternal behavior,
Davis, Collin   +3 more
core   +1 more source

Gender Is the Main Predictor of Wearing‐Off and Dyskinesia in Levodopa‐Naïve Patients with Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Evidence suggests that female gender represents a risk factor for the development of motor/nonmotor fluctuations and dyskinesia in Parkinson's disease (PD). So far, no prospective study has analyzed this aspect in relation to the introduction of levodopa treatment.
Maria Teresa Pellecchia   +41 more
wiley   +1 more source

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