Results 161 to 170 of about 589,499 (392)
Progress of non‐motor symptoms in early‐onset Parkinson's disease
Ibrain, EarlyView.This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView., 2023 Abstract Autism spectrum disorders (ASDs) are diagnosed in 1/100 children worldwide, based on two core symptoms: deficits in social interaction and communication, and stereotyped behaviours. G protein‐coupled receptors (GPCRs) are the largest family of cell‐surface receptors that transduce extracellular signals to convergent intracellular signalling ...
Anil Annamneedi +6 more
wiley +1 more source
The neuroleptic-like peptide desenkephalin-γ-endorphin does not antagonize the dopamine receptor agonist-induced inhibition of the release of [3H]dopamine from rat nucleus accumbens slices in vitro [PDF]
, 1987 F.S. Radhakishun +4 more
openalex +1 more source
Interdisciplinary Medicine, EarlyView.Left: The disruption of the balance between carcinogenic bacteria and probiotics mediated by antibiotics, protein, and glucose intake. Middle: The gut microbiota‐derived amino acids, primarily through tryptophan, tyrosine, arginine, and branched‐chain amino acid pathways, regulate glioma development via mechanisms such as AHR activation, metabolic ...
Qianquan Ma +10 more
wiley +1 more source
Gαq signalling from endosomes: A new conundrum
British Journal of Pharmacology, EarlyView., 2023 Abstract G‐protein‐coupled receptors (GPCRs) constitute the largest family of membrane receptors, and are involved in the transmission of a variety of extracellular stimuli such as hormones, neurotransmitters, light and odorants into intracellular responses.
Carole Daly, Bianca Plouffe
wiley +1 more source
Modulation of Adenylyl Cyclase Activity in Rat Striatal Homogenate by Dopaminergic Receptors
Journal of Pharmacological Sciences, 2008 We have characterized the modulation of adenylyl cyclase (AC) activity by ligands of dopaminergic receptors in rat striatal homogenate and compared the results with receptor-ligand binding affinities.
Argo Vonk, Reet Reinart, Ago Rinken
doaj
Glucose Abnormalities Associated to Prolactin Secreting Pituitary Adenomas
Frontiers in Endocrinology, 2019 The pathogenesis of obesity and alterations in glucose profile have been linked to PRL excess, as it is reportedly associated with metabolic syndrome in thereabout one third of patients.
Renata S. Auriemma +4 more
doaj +1 more source
Dopamine Inhibits Prolactin Secretion Stimulated by the Calcium Channel Agonist Bay-K-8644 through a Pertussis Toxin-Sensitive G Protein in Anterior Pituitary Cells* [PDF]
, 1988 A Enjalbert +5 more
openalex +1 more source
Dopamine agonists and the risk of cardiac-valve regurgitation.
New England Journal of Medicine, 2007 BACKGROUND Case reports and echocardiographic studies suggest that the ergot-derived dopamine agonists pergolide and cabergoline, used in the treatment of Parkinson's disease and the restless legs syndrome, may increase the risk of cardiac-valve ...
R. Schade +4 more
semanticscholar +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background The treatment of levodopa‐induced dyskinesia in Parkinson's disease (PD) is a largely unmet need. Objectives Mesdopetam is a novel small molecule dopamine D3 receptor antagonist aimed for the treatment of levodopa‐induced dyskinesia.
Angelo Antonini +6 more
wiley +1 more source