Results 91 to 100 of about 45,985 (264)

Molecularly Engineered Phenoxazinone‐Skeleton Cascade‐Activated NIR Probes for Monitoring Fe2+/Viscosity in Ferroptosis‐Mediated Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
A series of Fe2+/viscosity cascade‐activated NIR fluorescence probes (NP1–5) are synthesized, and NP3 is selected for its optimal properties. To verify application of NP3 in ferroptosis intervention in PD, PQR NPs, is constructed by NP3 and quercetin self‐assembling.
Lixia Guo   +11 more
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Multiparametric Bioresorbable Sensor for Doxorubicin Detection via Molecularly Imprinted Synthetic Receptors

open access: yesAdvanced Science, EarlyView.
A biodegradable molecularly imprinted polymer porous silica sensor enables dual optical readout of doxorubicin via fluorescence and effective optical thickness shifts. The combined transduction mechanisms provide enhanced reliability and quantitative accuracy over clinically relevant concentrations, representing a step toward transient implantable ...
Martina Corsi   +11 more
wiley   +1 more source

Ferroptosis Induction by Fenbendazole Combined With Photothermal Therapy Triggers Dual‐Immunotherapy Against Bladder Cancer

open access: yesAdvanced Science, EarlyView.
The novel intravesical delivery system exhibits GSH‐responsive drug release, enabling a synergistic therapeutic strategy that combines ferroptosis, ICD and PTT. ABSTRACT Ferroptosis, a newly recognized form of regulated cell death, has emerged as a promising strategy in cancer therapy.
Xiaojian Xu   +15 more
wiley   +1 more source

Electron Delocalization Induced by 3d–4f Orbital Hybridization of Co─Ce Atom Pairs Toward Enhanced Electromagnetic Wave Attenuation and Antibacterial Performance

open access: yesAdvanced Science, EarlyView.
Co─Ce dual atomic configuration anchored on the surface of NC matrix has been constructed to regulate the local electron structure. The higher occupied states induced by the Co 3d‐Ce 4f orbital hybridization facilitate the formation of polarized electric fields, which in turn strengthens the polarization relaxation and partially repairs the effective ...
Da Li   +8 more
wiley   +1 more source

Proof-of-Concept Development of a Bioelectric Biosensor Using Arduino for Monitoring Dopaminergic Response in Neuroblastoma Cells

open access: yesMicromachines
This study presents the proof-of-concept design and preliminary implementation of a bioelectric biosensor based on an Arduino platform for real-time monitoring of gel-immobilized N2a neuroblastoma cells using dopamine as a model neurotransmitter.
Magdalene Pappa, Spyridon Kintzios
doaj   +1 more source

Neuromodulator Dynamics Underlying Associative Learning in the Ventral Striatum's Olfactory Tubercle

open access: yesAdvanced Science, EarlyView.
Using fiber photometry and genetically encoded sensors, the dynamic release patterns of four neuromodulators in the olfactory tubercle (OT)—a brain region overlapping with the olfactory cortex and ventral striatum—were systematically monitored in response to external rewards and distinct reward‐associated learning processes.
Maojun Hong   +7 more
wiley   +1 more source

Heterointerface‑Enabled Electrocatalysis for Efficient Energy Conversion

open access: yesAdvanced Science, EarlyView.
Functionally distinct A/B materials can be integrated at the nanoscale to create customized heterointerfaces with tunable band alignment and charge redistribution, providing fast electron and ion transport channels as well as cooperative dual active sites.
Liuru Fang   +3 more
wiley   +1 more source

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