Results 21 to 30 of about 862,104 (211)

The dopaminergic system is able to modulate the central histamine-induced pressor effect in hemorrhage-shocked rats

Annales Academiae Medicae Silesiensis
Introduction: Histamine administered intracerebroventricularly (icv) induces a resuscitating effect in hemorrhage-shocked rats. Dopamine receptors are present in neuronal pathways involved in central cardiovascular regulation; therefore, the aim of the ...
Karolina Jasikowska, Magdalena Zając, Alessandra Ottani, Daniela Giuliani , Salvatore Guarini, Jerzy Jochem   +5 more
doaj   +1 more source

A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research

Frontiers in Pharmacology, 2018
The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of their anti-emetic properties and repurposing from one indication to another is a continuing trend.
Gareth J. Sanger, Paul L. R. Andrews
doaj   +1 more source

Oculogyric crisis induced by risperidone in a child with GRIN1 variant

Brain Disorders, 2023
The GluN1 subunit of the N-methyl-d-aspartate (NMDA) receptor is encoded by GRIN1 gene. Mutations in this gene can cause neurodevelopmental disorders with or without hyperkinetic movements and seizures.
Ali Mir, Montaha Almudhry, Shahid Bashir, Hamoud Khallaf   +3 more
doaj   +1 more source

A Role for Sigma Receptors in Stimulant Self Administration and Addiction

Pharmaceuticals, 2011
Sigma1 receptors (σ1Rs) represent a structurally unique class of intracellular proteins that function as chaperones. σ1Rs translocate from the mitochondria-associated membrane to the cell nucleus or cell membrane, and through protein-protein interactions
Shang-Yi Tsai, Theresa Kopajtic, Takato Hiranita, Teruo Hayashi, Gianluigi Tanda, Jonathan L. Katz, Tsung-Ping Su   +6 more
doaj   +1 more source

Perioperative utility of amisulpride and dopamine receptor antagonist antiemetics-a narrative review

Frontiers in Pharmacology, 2023
Despite advances in antiemetics and protocolized postoperative nausea vomiting (PONV) management, it remains one of the most common postoperative adverse events.
Murad Elias, Alexa Gombert, Sulaimaan Siddiqui, Sun Yu, Zhaosheng Jin, Sergio Bergese   +5 more
doaj   +1 more source

Managing and treating Sydenham chorea: A systematic review

Brain and Behavior, 2023
Introduction Sydenham's chorea (SC), prevalent in developing countries and occasionally affecting developed ones, poses a clinical challenge due to the lack of systematic guidelines for diagnosis and treatment.
Samiuddin Tariq, Faizan Niaz, Summaiyya Waseem, Taha Gul Shaikh, Syed Hassan Ahmed, Muhammad Irfan, Abdulqadir J. Nashwan, Irfan Ullah   +7 more
doaj   +1 more source

Effects of Intra-BLA Administration of PPAR Antagonists on Formalin-Evoked Nociceptive Behaviour, Fear-Conditioned Analgesia, and Conditioned Fear in the Presence or Absence of Nociceptive Tone in Rats

Molecules, 2022
There is evidence for the involvement of peroxisome proliferator-activated receptors (PPARs) in pain, cognition, and anxiety. However, their role in pain–fear interactions is unknown.
Jessica C. Gaspar, Bright N. Okine, David Dinneen, Michelle Roche, David P. Finn   +4 more
doaj   +1 more source

Effects of dopamine D2 receptor partial agonist antipsychotic aripiprazole on dopamine synthesis in human brain measured by PET with L-[β-11C]DOPA. [PDF]

PLoS ONE, 2012
Dopamine D(2) receptor partial agonist antipsychotic drugs can modulate dopaminergic neurotransmission as functional agonists or functional antagonists.
Hiroshi Ito, Harumasa Takano, Ryosuke Arakawa, Hidehiko Takahashi, Fumitoshi Kodaka, Keisuke Takahata, Tsuyoshi Nogami, Masayuki Suzuki, Tetsuya Suhara   +8 more
doaj   +1 more source

An Extremely Rare Case of Gastroptosis Treated Successfully with Itopride in a Patient with Parkinson’s Disease

Nigerian Postgraduate Medical Journal
A rare condition known as gastroptosis causes the major curvature of the stomach to shift downward and towards the pelvis. While some are asymptomatic, others experience symptoms. Cross-sectional imaging, or barium X-rays, are diagnostic.
Kübra Yildiz Cömert, Alper Tuna Güven
doaj   +1 more source

Effect of best practice advisory on the administration of contraindicated medications to hospitalized patients with Parkinson’s disease and related disorders

Frontiers in Aging Neuroscience, 2023
ObjectiveTo determine the effect of a Best Practice Advisory (BPA) on the ordering and administration of contraindicated dopamine blocking agents (DBA) to hospitalized patients with Parkinson’s disease (PD) and related disorders.BackgroundPatients with ...
Natalia Chunga, Katherine Amodeo, Katherine Amodeo, Melanie Braun, Blanca Y. Valdovinos, Irene H. Richard, Irene H. Richard   +6 more
doaj   +1 more source