Results 51 to 60 of about 282,920 (297)

Programming Neuromorphic Plasticity Through Ionic and Electronic Coupling in Organic Electrochemical Transistors

Advanced Functional Materials, EarlyView.
Neuromorphic plasticity in OECTs is governed by the post‐stimulus evolution of coupled ionic and electronic states. Semiconductor chemistry and morphology, electrolyte composition and interfaces, and device architecture regulate ion injection, transport, confinement, and release, shifting responses from rapidly relaxing STP to metastable memory and ...
Inho Lee, Hyoik Jang, Ji Hwan Kim, Jonghyun Won, Namhee Kim, Wonseok Shin, Giwon Lee, Eunho Lee, Daegun Kim, Sungjun Park   +9 more
wiley   +1 more source

Effect of intermittent subchronic MK‐801 administration on dopamine synthesis capacity and responsiveness in the prefrontal cortex

Neuropsychopharmacology Reports
Aim The therapeutic potential of N‐methyl‐D‐aspartate glutamate receptor (NMDAR) antagonists, particularly ketamine, in mood disorders, is linked to their modulation of dopamine dynamics in the medial prefrontal cortex (mPFC).
Kazuro Shibata, Kosuke Enomoto, Takahiro Tsutsumi, Hiroyuki Muraoka, Tatsu Fuwa, Masahiko Kawano, Jun Ishigooka, Ken Inada, Katsuji Nishimura, Hidehiro Oshibuchi   +9 more
doaj   +1 more source

Management of Acute Migraine in Children

Pediatric Neurology Briefs, 2007
The management of acute pediatric migraine headaches in the pediatric emergency department (ED) and in a mixed pediatric and adult ED was compared at the University of Alberta, Edmonton, Canada.
J Gordon Millichap
doaj   +1 more source

Effects of Intra-BLA Administration of PPAR Antagonists on Formalin-Evoked Nociceptive Behaviour, Fear-Conditioned Analgesia, and Conditioned Fear in the Presence or Absence of Nociceptive Tone in Rats

Molecules, 2022
There is evidence for the involvement of peroxisome proliferator-activated receptors (PPARs) in pain, cognition, and anxiety. However, their role in pain–fear interactions is unknown.
Jessica C. Gaspar, Bright N. Okine, David Dinneen, Michelle Roche, David P. Finn   +4 more
doaj   +1 more source

Digitally Printed Eco‐Friendly Electronic Devices

Advanced Functional Materials, EarlyView.
Fabrication of electronics using eco‐friendly materials through digital printing routes is a promising strategy for improving life cycle sustainability and reducing the environmental impacts of conventional manufacturing. This review highlights state‐of‐the‐art eco‐friendly materials, green ink formulations, various resource‐efficient digital printing ...
Nitheesh M. Nair, Mikel Rincón‐Iglesias, Cristian Mendes‐Felipe, Fatemeh Etehadi, Senentxu Lanceros‐Méndez, Gerardo Hernandez‐Sosa   +5 more
wiley   +1 more source

synthesis and pharmacological characterization of silicon-containing muscarinic antagonists, dopamine receptor antagonists, Ca2+ channel blockers, and alpha1-adrenoceptor antagonists

, 2004
Im Rahmen der vorliegenden Arbeit wurden neuartige siliciumhaltige Muscarinrezeptor-Antagonisten, Dopaminrezeptor-Antagonisten, Ca2+-Kanal-Blocker sowie alpha1-Rezeptor-Antagonisten synthetisiert, welche Sila-Analoga (C/Si-Austausch) bekannter ...
Heinrich, Tilman
core   +2 more sources

Adenosine A𝟐A Receptor Antagonists Do Not Disrupt Rodent Prepulse Inhibition: An Improved Side Effect Profile in the Treatment of Parkinson's Disease

Parkinson's Disease, 2012
Parkinson's disease (PD) is characterized by loss of dopaminergic neurons in the substantia nigra. Current treatments for PD focus on dopaminergic therapies, including L-dopa and dopamine receptor agonists.
Carina J. Bleickardt, Abigail L. LaShomb, Carrie E. Merkel, Robert A. Hodgson   +3 more
doaj   +1 more source

Chronic A2A antagonist treatment alleviates parkinsonian locomotor deficiency in MitoPark mice

Neurobiology of Disease, 2010
Adenosine A2A receptor (A2AR) antagonists are being investigated as promising treatment strategy for Parkinson's disease (PD). To test whether A2AR antagonists are beneficial in early PD stages we used MitoPark mice, a genetic model with gradual ...
Daniel Marcellino, Eva Lindqvist, Marion Schneider, Christa E. Müller, Kjell Fuxe, Lars Olson, Dagmar Galter   +6 more
doaj   +1 more source

PDE10A Inhibitors—Clinical Failure or Window Into Antipsychotic Drug Action?

Frontiers in Neuroscience, 2021
PDE10A, a phosphodiesterase that inactivates both cAMP and cGMP, is a unique signaling molecule in being highly and nearly exclusively expressed in striatal medium spiny neurons.
Frank S. Menniti, Thomas A. Chappie, Christopher J. Schmidt   +2 more
doaj   +1 more source

Material Coupling in Hybrid Neuromorphic Devices: From Fundamentals to System‐Level Applications

Advanced Functional Materials, EarlyView.
Hybrid neuromorphic devices utilize heterointerfaces between emerging semiconductors, where charge transfer and trapping, ion or defect modulation, and photogating are translated into synaptic functions. This paper discusses coupling strategies that tailor interfacial electronic and ionic properties in organic semiconductors, metal oxides, two ...
Minsu So, Sunwoo Jeong, Youngmin Han, Fabrizio Torricelli, Hocheon Yoo, Junhwan Choi   +5 more
wiley   +1 more source