Results 171 to 180 of about 156,081 (291)

Fine-tuning of dopamine receptor signaling with aripiprazole counteracts ketamine's dissociative action, but not its antidepressant effect. [PDF]

Transl Psychiatry
Nakatsuka D, Suwa T, Deguchi Y, Fujita Y, Tashima R, Ohnami S, Kawashima H, Oishi N, Ogawa K, Yamakawa H, Murai T.   +10 more
europepmc   +1 more source

Regulation Mechanism of Dopamine Receptor 1 in Low Temperature Response of Marsupenaeus japonicus. [PDF]

Int J Mol Sci, 2023
Ren X, Bian X, Shao H, Jia S, Yu Z, Liu P, Li J, Li J.   +7 more
europepmc   +1 more source

Dopamine Receptor Enhancement [PDF]

, 1980
C. W. M. Whitty
openalex   +1 more source

In vivo toxic and lethal cardiorespiratory effects of a synthetic quaternary ammonium salt derivative of haloperidol in mice

Animal Models and Experimental Medicine, EarlyView.
Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao, Binger Lu, Jinhua Yang, Xiaowan Wang, Shuxian Li, Hongbo Fu, Fenfei Gao   +6 more
wiley   +1 more source

Dopamine-driven increase in IL-1β in myeloid cells is mediated by differential dopamine receptor expression and exacerbated by HIV. [PDF]

J Neuroinflammation
Matt SM, Nolan R, Manikandan S, Agarwal Y, Channer B, Oteju O, Daniali M, Canagarajah JA, LuPone T, Mompho K, Runner K, Nickoloff-Bybel E, Li B, Niu M, Schlachetzki JCM, Fox HS, Gaskill PJ.   +16 more
europepmc   +1 more source

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

Animal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran   +13 more
wiley   +1 more source

Synthesis and Characterization of Photoswitchable Covalent Ligands for the β2‐Adrenoceptor

Angewandte Chemie, EarlyView.
A structure‐based design of a covalent photoswitchable ligand for the β2‐adrenergic receptor, a therapeutically relevant GPCR, is described. This tool facilitates the modification of the intrinsic activity of the protein by light. Computational analysis of its mechanism of action suggests that the photoswitch takes place within the binding pocket ...
Ulrike Wirth, Eduard Neu, Davide Provasi, Steffen Feustel, Maximilian F. Schmidt, Harald Hübner, Dorothée Weikert, Marta Filizola, Burkhard König, Peter Gmeiner   +9 more
wiley   +2 more sources

CHL1 depletion affects dopamine receptor D2-dependent modulation of mouse behavior. [PDF]

Front Behav Neurosci, 2023
Fernandes L, Kleene R, Congiu L, Freitag S, Kneussel M, Loers G, Schachner M.   +6 more
europepmc   +1 more source

Characterization, solubilization, and separation of two distinct dopamine receptors in canine caudate nucleus.

, 1980
Koji Nishikori, Osamu Noshiro, K. Sano, Hiroo Maeno   +3 more
openalex   +1 more source

DOPAMINE RECEPTORS (DR) IN DOG INTRARENAL ARTERIES(IRA) [PDF]

, 1984
Robin A. Felder, John J. Worthington, Pedro A. José   +2 more
openalex   +1 more source