Results 181 to 190 of about 156,081 (291)

Disruption of the blood–brain barrier contributes to neurobehavioral changes observed in rheumatic heart disease

Animal Models and Experimental Medicine, EarlyView.
Sydenham's chorea (SC) is the neurological manifestation associated with acute rheumatic fever (ARF), triggered by a group A streptococcal (GAS) infection. Anti‐GAS antibodies cross‐reacting with tissue proteins are implicated in the development of neurological changes. In this study, using an animal model, we demonstrate that a compromised blood–brain
Rukshan Ahamed Mohamed Rafeek, Riya Thapa, Samarjeet Saluja, Bipandeep Banga, David McMillan, Kadaba Sri Sriprakash, Nicholas M. Andronicos, Adam Hamlin, Natkunam Ketheesan   +8 more
wiley   +1 more source

Gem‐Diboronic Acids: A Motif for Anion Recognition in Competitive Media

Angewandte Chemie, EarlyView.
Gem‐diboronic acids are an anion recognition motif that provides strong and directional binding to oxoanions in aqueous media. This motif provides a selectivity profile that is distinct from other anion recognition groups, and binding affinities that are superior to those of simple amides and (thio)ureas.
Stephen M. Butler, Daniel M. Beagan, William Lewis, Nathaniel K. Szymczak, Katrina A. Jolliffe   +4 more
wiley   +2 more sources

Natural Product-Inspired Dopamine Receptor Ligands. [PDF]

J Med Chem
Dorogan M, Namballa HK, Harding WW.
europepmc   +1 more source

Validating the Accuracy of Parkinson's Disease Clinical Diagnosis: A UK Brain Bank Case–Control Study

Annals of Neurology, EarlyView.
Objective Despite diagnostic criteria refinements, Parkinson's disease (PD) clinical diagnosis still suffers from a not satisfying accuracy, with the post‐mortem examination as the gold standard for diagnosis. Seminal clinicopathological series highlighted that a relevant number of patients alive‐diagnosed with idiopathic PD have an alternative post ...
Lazzaro di Biase, Pasquale Maria Pecoraro, Vincenzo Di Lazzaro   +2 more
wiley   +1 more source

Anti-dopamine receptor 2 antibody encephalitis in adults: a case report. [PDF]

BMC Neurol
Wu X, Shi M, Zhang H.
europepmc   +1 more source

A novel dopamine receptor D2 antagonist (ONC206) potentiates the effects of olaparib in endometrial cancer. [PDF]

Cancer Biol Ther, 2023
Paraghamian SE, Qiu J, Hawkins GM, Zhao Z, Sun W, Fan Y, Zhang X, Suo H, Hao T, Prabhu VV, Allen JE, Zhou C, Bae-Jump V.   +12 more
europepmc   +1 more source

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features

Annals of Neurology, EarlyView.
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner, Eliza Honybun, Melanie Bahlo, Karen L. Oliver, Ingrid E. Scheffer   +4 more
wiley   +1 more source

Optogenetic Control of Dopamine Receptor 2 Reveals a Novel Aspect of Dopaminergic Neurotransmission in Motor Function. [PDF]

J Neurosci
Kim H, Park G, Shin HG, Kwon D, Kim H, Baek IY, Nam MH, Cho IJ, Kim J, Seong J.   +9 more
europepmc   +1 more source

Dopamine receptor activation regulates reward expectancy signals during cognitive control in primate prefrontal neurons. [PDF]

Nat Commun, 2023
Ott T, Stein AM, Nieder A.
europepmc   +1 more source

Involvement of Phospholipids in the Coupling of Adenosine and Dopamine Receptors to Rat Striatal Adenylate Cyclase

, 1982
Madhu B. Anand‐Srivastava, Roger A. Johnson   +1 more
openalex   +1 more source