Results 11 to 20 of about 1,589,779 (294)
Tetrahydrocannabinol and dopamine D1 receptor [PDF]
Frontiers in Neuroscience, 2023 Dopamine, a neurotransmitter and neuromodulator, is primarily released by dopaminergic neurons in the midbrain, particularly in the substantia nigra and the ventral tegmental area (VTA). Dopamine is known to have 5 receptors which are D1, D2, D3, D4 and D5, which are further categorized into 2 families: D1 family and D2 family.
Jiwon, Lee
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Receptores de dopamina y heterómeros de receptores de dopamina en la modulación de la neurotransmisión [PDF]
, 2012 [spa] La mayoría de los ligandos de GPCR que actúan como agonistas, antagonistas o agonistas inversos, se unen al mismo dominio del receptor reconocido por los agonistas endógenos, es decir, el lugar de unión ortostérico.
González González, Sergio
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Dopamine Receptor Signaling [PDF]
Journal of Receptors and Signal Transduction, 2004 The D1-like (D1, D5) and D2-like (D2, D3, D4) classes of dopamine receptors each has shared signaling properties that contribute to the definition of the receptor class, although some differences among subtypes within a class have been identified. D1-like receptor signaling is mediated chiefly by the heterotrimeric G proteins Galphas and Galphaolf ...
Kim A, Neve +2 more
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Japanese Journal of Pharmacology, 2000 Initial investigations on dopamine D4 receptors generated much interest in the role of this receptor in schizophrenia and other aspects of human behavior, as well as new opportunities for novel therapeutics. However, attempts to treat patients suffering from schizophrenia with dopamine D4 agents have failed to yield satisfactory results so far.
M. Helmeste, Daiga, Wa Tang, Siu
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Heteromerización de receptores de adenosina A2A, dopamina D2 y cannabinoides CB1. Implicaciones farmacológicas y funcionales. [PDF]
, 2007 [spa] La visión de los receptores acoplados a proteína G ha evolucionado en los últimos años. Clásicamente se consideraban unidades individuales capaces de producir una señal intracelular; actualmente, está aceptado que estas proteínas de membrana pueden
Carriba Domínguez, Paulina
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Antipsychotic Induced Dopamine Receptor Supersensitivity and It’s Clinical Implications
Jurnal Psikiatri Surabaya, 2022 Background : Schizophrenia is a serious mental disorder that requires multi-modal and continuous treatment, mainly with antipsychotic. Along with the increasing life expectancy of schizophrenic patients, various problems due to prolonged blocking of ...
Riko Lazuardi, Khairina Rina, Dianasari
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European Journal of Inflammation, 2009 We investigated dopamine receptor gene expression in peripheral blood mononuclear cells of schizophrenic patients before and after treatment. Also dopamine receptor genes expression profile was compared in two treatment groups including haloperidol and ...
G.H. Shariati +4 more
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Sensors, 2008 In the striatum many neurotransmitters including GABA, glutamate, acetylcholine, dopamine, nitric oxide and adenosine interact to regulate synaptic transmission. Dopamine release in the striatum is regulated by a number of pre- and postsynaptic receptors
Carmel O’Neill +1 more
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BMC Musculoskeletal Disorders, 2011 Background Control of skeletal muscle mass and force production is a complex physiological process involving numerous regulatory systems. Agents that increase skeletal muscle cAMP levels have been shown to modulate skeletal muscle mass and force ...
Dietrich Jeffrey A +6 more
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Frontiers in Cellular Neuroscience, 2022 Structural plasticity changes in the brain are thought to underlie, at least partially, drug-induced persistent changes in behavior. Our previous study reported that increased synaptic density in the nucleus accumbens shell (NAcsh) correlates with and ...
Shuai Wang +14 more
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