Results 31 to 40 of about 1,589,779 (294)

Novel Mutation Detection of Regulatory Molecule Dopamine Gene Receptors (D1–D5) Encoding Analysis on Human Peripheral Blood Lymphocytes in Schizophrenia Patients

open access: yesEuropean Journal of Inflammation, 2009
There is much evidence which highlights the involvement of the dopamine system in the pathophysiology of schizophrenia. Recently, there have been reports of detected mutations in dopamine gene receptors in genomic DNA of schizophrenia.
G. Ahangari MT, PhD   +4 more
doaj   +1 more source

Brain Dopamine Transmission in Health and Parkinson's Disease: Modulation of Synaptic Transmission and Plasticity Through Volume Transmission and Dopamine Heteroreceptors

open access: yesFrontiers in Synaptic Neuroscience, 2018
This perspective article provides observations supporting the view that nigro-striatal dopamine neurons and meso-limbic dopamine neurons mainly communicate through short distance volume transmission in the um range with dopamine diffusing into ...
Dasiel O. Borroto-Escuela   +17 more
doaj   +1 more source

Change of dopamine receptor mRNA expression in lymphocyte of schizophrenic patients

open access: yesBMC Medical Genetics, 2001
Background Though the dysfunction of central dopaminergic system has been proposed, the etiology or pathogenesis of schizophrenia is still uncertain partly due to limited accessibility to dopamine receptor. The purpose of this study was to define whether
Choi Chul-Hee   +3 more
doaj   +1 more source

Tumor suppression and improvement in immune systems by specific activation of dopamine D1-receptor-expressing neurons in the nucleus accumbens

open access: yesMolecular Brain, 2022
Recent research has suggested that the mesolimbic dopamine network that mainly terminates in the nucleus accumbens may positively control the peripheral immune system.
Daisuke Sato   +12 more
doaj   +1 more source

Dopamine Receptors and Neurodegeneration [PDF]

open access: yesAging and disease, 2015
Dopamine (DA) is one of the major neurotransmitters and participates in a number of functions such as motor coordination, emotions, memory, reward mechanism, neuroendocrine regulation etc. DA exerts its effects through five DA receptors that are subdivided in 2 families: D1-like DA receptors (D1 and D5) and the D2-like (D2, D3 and D4). All DA receptors
Claudia, Rangel-Barajas   +2 more
openaire   +2 more sources

Cardiovascular Dopamine Receptors: Role of Renal Dopamine and Dopamine Receptors in Sodium Excretion [PDF]

open access: yesPharmacology & Toxicology, 1990
Research efforts in the area of peripheral dopamine have now established the presence of two distinct subtypes--DA1 and DA2--of DA receptors, and have identified a potential role for dopamine produced within the kidney in the control of renal sodium excretion.
M F, Lokhandwala, S S, Hegde
openaire   +2 more sources

Conformation of dopamine at the dopamine receptor. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1978
Tritiated dopamine was used to label the dopamine receptor in membranes isolated from the rat corpus striatum. Scatchard analysis of displacement of [3H]dopamine by nonradioactive dopamine indicated the presence of two binding sites. The similarities in affinity, capacity, and drug specificity of the high-affinity site in the striatal membranes from ...
H L, Komiskey   +3 more
openaire   +2 more sources

Activation of Dopamine D4 Receptors Is Protective Against Hypoxia/ Reoxygenation-Induced Cell Death in HT22 Cells

open access: yesJournal of Pharmacological Sciences, 2010
Several reports have shown that some dopamine receptor ligands modulate the ischemia–reperfusion injury in animal models; however, its underling mechanisms are still unclear. In this study, we sought to establish an in vitro experimental model of hypoxia/
Saori Shimada   +5 more
doaj   +1 more source

Dopamine receptor subtypes and ingestive behaviour [PDF]

open access: yes, 1999
Both centrally and systemically administered dopamine agonists and antagonists decrease ingestive behaviour. The aim of this thesis was to examine whether drugs acting at different receptor subtypes decreased intake in different ways.
Genn, Rachel F., Genn, R.F.
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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