Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt
As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez +5 more
wiley +1 more source
The Heteromeric Dopamine Receptor D2:D3 Controls the Gut Recruitment and Suppressive Activity of Regulatory T-Cells. [PDF]
Mora J +13 more
europepmc +1 more source
Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort
Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov +42 more
wiley +1 more source
Mapping the cellular basis of species differences in oxytocin and dopamine receptor expression in the vole nucleus accumbens. [PDF]
Loth MK +7 more
europepmc +1 more source
D2Dopamine Receptor-Mediated Modulation of Voltage-Dependent Na+Channels Reduces Autonomous Activity in Striatal Cholinergic Interneurons [PDF]
Nicolas Maurice +6 more
openalex +1 more source
Brain region-specific dopamine receptor changes and astrocyte activation influence tau pathology through CDK5 in Alzheimer's disease models. [PDF]
Singh S, Kumar U.
europepmc +1 more source
Smoking Modulation of μ-Opioid and Dopamine D2 Receptor-Mediated Neurotransmission in Humans [PDF]
David Scott +6 more
openalex +1 more source
Sleep Deprivation in Rats Causes Dissociation of the Synaptic NMDA Receptor/D1 Dopamine Receptor Heterocomplex. [PDF]
Kiknadze N +8 more
europepmc +1 more source

