Results 261 to 270 of about 303,848 (355)
Differential visualization of dopamine D2 and D3 receptors in rat brain
Bruce Parsons +2 more
openalex +1 more source
ABSTRACT In Attention Deficit Hyperactivity Disorder (ADHD), methylphenidate is one of the most widely used drugs, in which patient response significantly impacts prognosis. This study aimed to characterize the molecular profile of 10 genes associated with methylphenidate therapy.
Aline Pasquini Santos +14 more
wiley +1 more source
Haloperidol dopamine receptor occupancy and antagonism correspond to delirium agitation scores and EPS risk: A PBPK-PD modeling analysis. [PDF]
Burkat PM.
europepmc +1 more source
Amantadine (AMA) regulates neurocyte apoptosis and inhibits neurocyte inflammation to prevent maternal immune activation (MIA) from affecting offspring behavior. Abstract Background Maternal viral infection during pregnancy can lead to maternal immune activation (MIA), increasing the risk of neurodevelopmental disorders in offspring.
Jianfei Wu +8 more
wiley +1 more source
Hyperactive mTORC1 in striatum dysregulates dopamine receptor expression and odor preference behavior. [PDF]
Chen L +4 more
europepmc +1 more source
Objective The objective of this study was to investigate the relationships among subthalamic nucleus (STN) activity, gait initiation (GI), and freezing of gait (FOG) in patients with Parkinson's disease (PD). Methods We recorded GI and STN local field potentials (LFPs) via externalized cables in 38 patients with PD (35 reporting FOG in daily life ...
Antoine Collomb‐Clerc +12 more
wiley +1 more source
Roles and Mechanisms of Dopamine Receptor Signaling in Catecholamine Excess Induced Endothelial Dysfunctions. [PDF]
Yang Z +12 more
europepmc +1 more source
Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy
Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam +29 more
wiley +1 more source
Imipridones and Dopamine Receptor Antagonism in the Therapeutic Management of Gliomas. [PDF]
Burton E +4 more
europepmc +1 more source

