Results 81 to 90 of about 156,081 (291)

Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin   +8 more
wiley   +1 more source

High‐Sensitivity Dopamine Detection with Copper Terephthalate‐Modified Carbon Electrode

open access: yesAdvanced Sensor Research, EarlyView.
This work introduces a facile synthesis of a copper‐terephthalate with a flake‐like morphology and layered topology. The Cu‐BDC demonstrates exceptional performance as a glassy carbon electrode modifier, enabling highly sensitive and reliable dopamine detection.
Aleksander Ejsmont   +3 more
wiley   +1 more source

Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration

open access: yesAdvanced Therapeutics, EarlyView.
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana   +5 more
wiley   +1 more source

Distinct roles of presynaptic dopamine receptors in the differential modulation of the intrinsic synapses of medium-spiny neurons in the nucleus accumbens

open access: yesBMC Neuroscience, 2007
Background In both schizophrenia and addiction, pathological changes in dopamine release appear to induce alterations in the circuitry of the nucleus accumbens that affect coordinated thought and motivation. Dopamine acts principally on medium-spiny GABA
Schmauss Claudia   +2 more
doaj   +1 more source

Upconversion‐Based Remote Deep Brain Modulation for Therapeutic Dissection of Parkinson's Disease

open access: yesAdvanced Therapeutics, EarlyView.
An upconversion‐based wireless optogenetic strategy enables an all‐optical deep brain modulation solution for treating Parkinson's disease in rodent animals without using electronics or any tethered cables, providing experimental evidence supporting a therapeutic mechanism of STN‐DBS by disruption of anterograde signal transmission along the indirect ...
Wenchong Zhang   +13 more
wiley   +1 more source

Toward molecular neuroeconomics of obesity [PDF]

open access: yesarXiv, 2011
Because obesity is a risk factor for many serious illnesses such as diabetes, better understandings of obesity and eating disorders have been attracting attention in neurobiology, psychiatry, and neuroeconomics. This paper presents future study directions by unifying (i) economic theory of addiction and obesity (Becker and Murphy, 1988; Levy 2002 ...
arxiv  

Blockage of narcotic-induced dopamine receptor supersensitivity by cyclo(Leu-Gly). [PDF]

open access: green, 1979
Ronald F. Ritzmann   +3 more
openalex   +1 more source

Polydopamine Nanohydrogel Decorated Adhesive and Responsive Hierarchical Microcarriers for Deafness Protection

open access: yesAdvanced Science, EarlyView.
A type of polydopamine (PDA) nanogel decorated adhesive and responsive hierarchical microcarriers for ALA delivery and deafness prevention. PDA@microcarriers can protect the encapsulated drugs from external disturbances and prolong their retention time in the inner ear.
Hong Chen   +8 more
wiley   +1 more source

Dopamine agonists in Parkinson’s disease: Impact of D1-like or D2-like dopamine receptor subtype selectivity and avenues for future treatment

open access: yesClinical Parkinsonism & Related Disorders, 2023
Dopamine agonists (DAs) have demonstrated efficacy for the treatment of Parkinson’s disease (PD) but are limited by adverse effects (AEs). DAs can vary considerably in their receptor subtype selectivity and affinity, chemical composition, receptor ...
Stuart H. Isaacson   +4 more
doaj  

Molecular De Novo Design through Deep Reinforcement Learning [PDF]

open access: yesarXiv, 2017
This work introduces a method to tune a sequence-based generative model for molecular de novo design that through augmented episodic likelihood can learn to generate structures with certain specified desirable properties. We demonstrate how this model can execute a range of tasks such as generating analogues to a query structure and generating ...
arxiv  

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