Results 81 to 90 of about 303,848 (355)

Orexin-Corticotropin-Releasing Factor Receptor Heteromers in the Ventral Tegmental Area as Targets for Cocaine [PDF]

open access: yes, 2015
Release of the neuropeptides corticotropin-releasing factor (CRF) and orexin-A in the ventral tegmental area (VTA) play an important role in stress-induced cocaine-seeking behavior.
Aguinaga, David   +17 more
core   +1 more source

Biosupercapacitors for Human‐Powered Electronics

open access: yesAdvanced Functional Materials, EarlyView.
Biosupercapacitors are emerging as biocompatible and integrative energy systems for next‐generation bioelectronics, offering rapid charge–discharge performance and mechanical adaptability. This review systematically categorizes their applications from external to organ‐level systems and highlights their multifunctional roles in sensing, actuation, and ...
Suhyeon Kim   +7 more
wiley   +1 more source

Heteroreceptor complexes and their allosteric receptor-receptor interactions in the central nervous system. Focus on examples from Dopamine D2 and Serotonin 5-HT1a receptors [PDF]

open access: yes, 2018
GPCR interacting proteins (specially β- arrestin) and their receptor-protein interactions are also covered but their interactions with the allosteric receptor-receptor interactions in heteroreceptor complexes remain to be elucidated.
Corrales Ferro, Fidel
core   +1 more source

Nanoparticles Decorated Nanotubes: Advanced Local Therapies From Anodized Nanoengineered Titanium Implants

open access: yesAdvanced Functional Materials, EarlyView.
This comprehensive review explores therapeutic titanium implants designed to enhance integration and provide superior antibacterial efficacy. It is focused on anodized titanium implants with titania nanotubes (TNTs) loaded with nanoparticles (NPs) for local therapeutic release, enhancing bioactivity and bactericidal functions.
Divya Chopra   +5 more
wiley   +1 more source

Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence

open access: yesFrontiers in Psychiatry, 2013
Cocaine addiction is accompanied by a decrease in striatal dopamine signaling, measured as a decrease in dopamine D2 receptor binding as well as blunted dopamine release in the striatum. These alterations in dopamine transmission have clinical relevance,
Pierre eTrifilieff   +2 more
doaj   +1 more source

Dopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex [PDF]

open access: yes, 2001
Neuromodulators, like dopamine, have considerable influence on the\ud processing capabilities of neural networks. \ud This has for instance been shown in the working memory functions\ud of prefrontal cortex, which may be regulated by altering the\ud ...
Scheler, Gabriele
core  

Pharmacology of novel psychoactive substances [PDF]

open access: yes, 2016
This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Depression of Serotonin Synaptic Transmission by the Dopamine Precursor L-DOPA

open access: yesCell Reports, 2015
Imbalance between the dopamine and serotonin (5-HT) neurotransmitter systems has been implicated in the comorbidity of Parkinson’s disease (PD) and psychiatric disorders.
Stephanie C. Gantz   +4 more
doaj   +1 more source

D₂ Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways [PDF]

open access: yes, 2005
Regulator of G-protein signaling 9-2 (RGS9-2), a member of the RGS family of Gα GTPase accelerating proteins, is expressed specifically in the striatum, which participates in antipsychotic-induced tardive dyskinesia and in levodopa-induced dyskinesia. We
Axelrod, Jeffrey D.   +10 more
core  

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