Results 101 to 110 of about 48,073 (302)

Dopamine signaling in food addiction: role of dopamine D2 receptors

open access: yesBMB Reports, 2013
Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are widely believed to modify reward-related behaviors and are therefore closely associated with drug addiction.
openaire   +4 more sources

Polydopamine‐Coated Selenium Nanoparticles as a Stable Catalyst for Tunable and Sustained Nitric Oxide Generation

open access: yesSmall Science, EarlyView.
Polydopamine‐coated selenium nanoparticles (Se@PDA NPs) are effective catalysts for in situ NO generation. The PDA coating enhances cellular uptake, allowing for intracellular NO generation from endogenous NO donors, such as S‐nitrosoglutathione. Se@PDA NPs exhibit high biocompatibility, sustain NO generation over five doses, and remain active for at ...
Shu Geng   +4 more
wiley   +1 more source

Esophageal and Oropharyngeal Dysphagia: Clinical Recommendations From the United European Gastroenterology and European Society for Neurogastroenterology and Motility

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Dysphagia is a prevalent symptom of the upper gastrointestinal tract causing health related consequences, impacting quality of life and is associated with global economic burden. Swallowing difficulties are classified into oropharyngeal dysphagia (OD) and esophageal dysphagia.
Amir Mari   +45 more
wiley   +1 more source

Spasmodic Dysphonia

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Spasmodic dysphonia is a laryngeal dystonia that can present as adductor, abductor, or mixed types, with or without tremor. The etiology is not understood fully. Comprehensive evaluation is required to establish the diagnosis. Treatments include voice therapy, medications, botulinum toxin injection, laryngeal surgery, deep brain stimulation ...
Aaron J. Jaworek, Robert T. Sataloff
wiley   +1 more source

Not all partial dopamine D2 receptor agonists are the same in treating schizophrenia. Exploring the effects of bifeprunox and aripiprazole using a computer model of a primate striatal dopaminergic synapse

open access: yesNeuropsychiatric Disease and Treatment, 2010
Athan Spiros1, Robert Carr1, Hugo Geerts1,21In Silico Biosciences, Berwyn, PA, USA; 2School of Medicine, University of Pennsylvania, PA, USAAbstract: Species differences in physiology and unique active human metabolites contribute to the limited ...
Athan Spiros, Robert Carr, Hugo Geerts
doaj  

Current Insights Into Individualized Diagnosis and Treatment of Allergic Rhinitis Based on Phenotype and Endotype

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu   +7 more
wiley   +1 more source

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