A brain imaging study of dopamine receptor D2 availability in cannabis dependent users after recovery from cannabis-induced psychosis. [PDF]
Front Psychiatry, 2023 Weinstein AM.
europepmc +1 more source
Dissecting Dopamine D2 Receptor Signaling
, 2015 Dopamine D2 receptor (D2R) is a G protein-coupled receptor (GPCR) that activates G protein and arrestin signaling molecules. D2R antagonism has been a hallmark of antipsychotic medications for more than half a century. However, this drug-class is associated with substantial side effects that decrease quality of life and medication compliance.
openaire +2 more sources
Early adversity and the comorbidity between metabolic disease and psychopathology
The Journal of Physiology, EarlyView.Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas +1 more
wiley +1 more source
Expression, correlation, and prognostic significance of different nicotinic acetylcholine receptors, programed death ligand 1, and dopamine receptor D2 in lung adenocarcinoma. [PDF]
Front Oncol, 2022 Pal K +8 more
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Mitochondrial control of ciliary gene expression and structure in striatal neurons
The Journal of Physiology, EarlyView.Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen +5 more
wiley +1 more source
Neuropsychiatric Disease and Treatment, 2010 Athan Spiros1, Robert Carr1, Hugo Geerts1,21In Silico Biosciences, Berwyn, PA, USA; 2School of Medicine, University of Pennsylvania, PA, USAAbstract: Species differences in physiology and unique active human metabolites contribute to the limited ...
Athan Spiros, Robert Carr, Hugo Geerts
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Dopamine receptor D2, but not D1, mediates the reward circuit from the ventral tegmental area to the central amygdala, which is involved in pain relief. [PDF]
Mol Pain, 2022 Huang M +8 more
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Psychotropic medication and the fetal brain
The Journal of Physiology, EarlyView.Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
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The Redox Properties of Polyphenols and Their Role in ROS Generation for Biomedical Applications
Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.The dual redox nature of polyphenols enables antioxidant activity and controlled reactive oxygen species (ROS) generation. This review details the biomedical applications of polyphenols in materials such as nanoparticles, coatings, and hydrogels for antimicrobial, tissue regeneration, and cancer therapies.
Jose Bolaños‐Cardet +7 more
wiley +2 more sources
The Role of Dopamine Receptor D2 in Bridging the Intention-Behavior Gap in Sport Participation. [PDF]
Int J Environ Res Public Health, 2021 Park S +5 more
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