Developing Photoaffinity Probes for Dopamine Receptor D2 to Determine Targets of Parkinson's Disease Drugs. [PDF]
Kim ST+6 more
europepmc +1 more source
Coupling of D2 dopamine receptors to G-proteins in solubilized preparations of bovine caudate nucleus [PDF]
J. A. CHAZOT, Philip G. Strange
openalex +1 more source
Purine Metabolism and Dystonia: Perspectives of a Long‐Promised Relationship
Purine pool imbalance in purine metabolism disorders, such as Lesch–Nyhan disease, intersects with dystonia pathogenesis. The recent discovery of gain‐of‐function IMPDH2 pathogenic variants in patients with prominent dystonic manifestations provides new insights into the link between dystonia and purinergic system defects.
Ugo Sorrentino+4 more
wiley +1 more source
Heterogenous Dopamine D2 Receptor Subtype Messenger Ribonucleic Acid Expression in Clinically Nonfunctioning Pituitary Adenomas1 [PDF]
Ulrich Renner+8 more
openalex +1 more source
Role of Serum Brain‐Derived Neurotrophic Factor as a Biomarker of Chronic Pain in Older Adults
ABSTRACT Background Serum brain‐derived neurotrophic factor (BDNF) has emerged as a promising biomarker for chronic pain (CP) research and treatment. Yet, most human studies have been limited by small sample sizes, inadequate control of confounders and a lack of focus on sex and mental health differences.
R. Ortolá+9 more
wiley +1 more source
No association of dopamine D2 receptor molecular variant Cys311 and schizophrenia in Chinese patients [PDF]
Chia‐Hsiang Chen+2 more
openalex +1 more source
Astrocytes Mediate Psychostimulant‐Induced Alterations of Spike‐Timing Dependent Synaptic Plasticity
Main Points Cocaine and amphetamine stimulates astrocytes and downregulates the GLT‐1. The dysfunction in GLT‐1 modify EPSP kinetics and modulate STDP, switching LTP to LTD in psychostimulant‐treated mice. These effects were restored by upregulation of GLT‐1.
Samuel Alberquilla+7 more
wiley +1 more source
Effects of Tall Fescue Endophyte Type and Dopamine Receptor D2 Genotype on Cow-Calf Performance during Late Gestation and Early Lactation. [PDF]
Wilbanks SA+5 more
europepmc +1 more source
Predicting novel pharmacological activities of compounds using PubChem IDs and machine learning (CID-SID ML model) [PDF]
Significance and Object: The proposed methodology aims to provide time- and cost-effective approach for the early stage in drug discovery. The machine learning models developed in this study used only the identification numbers provided by PubChem.
arxiv