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Impulsiveness as the intermediate link between the dopamine receptor D2 gene and alcohol dependence
Psychiatric Genetics, 2003Objectives Reinforcement and reward processes have been proposed as being an intermediate link between the risk for alcohol dependence and the gene coding for the dopamine receptor D2 (DRD2).
F. Limosin +6 more
semanticscholar +1 more source
American journal of medical genetics, 2002
Association studies of the TaqI A allele of the dopamine receptor D2 (DRD2) gene with alcohol dependence have produced conflicting findings. Although a wide series of clinical features have been considered in the different association studies performed ...
F. Limosin +6 more
semanticscholar +1 more source
Association studies of the TaqI A allele of the dopamine receptor D2 (DRD2) gene with alcohol dependence have produced conflicting findings. Although a wide series of clinical features have been considered in the different association studies performed ...
F. Limosin +6 more
semanticscholar +1 more source
Population severance in manipur at dopamine receptor D2 locus.
Genetic Testing and Molecular Biomarkers, 2009INTRODUCTION Tibeto-Burman language-speaking Mongoloid groups of northeast India are reported to be genetically highly heterogeneous. Manipur, one of the states of this region sharing a major International border with Myanmar, is also expected to be ...
K. Saraswathy +10 more
semanticscholar +1 more source
Survey of Dopamine Receptor D2 Antagonists as Retinal Antifibrotics.
Journal of Ocular Pharmacology and TherapeuticsPurpose: To evaluate the potency and efficacy of a library of dopamine receptor D2 (D2R) antagonists in the mitigation of fibrotic activation in retinal pigment epithelial (RPE) cells. Methods: ARPE-19 cells were cultured and treated with methotrexate or
Ashley Y. Gao +4 more
semanticscholar +1 more source
D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons.
Science, 1990The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the substantia nigra. Severe movement disorders result from the loss of striatal dopamine in patients with Parkinson's disease ...
C. Gerfen +6 more
semanticscholar +1 more source
Archives of General Psychiatry, 1992
Positron emission tomography and selective radioligands were used to determine D1 and D2 dopamine receptor occupancy induced by neuroleptics in the basal ganglia of drug-treated schizophrenic patients.
L. Farde +5 more
semanticscholar +1 more source
Positron emission tomography and selective radioligands were used to determine D1 and D2 dopamine receptor occupancy induced by neuroleptics in the basal ganglia of drug-treated schizophrenic patients.
L. Farde +5 more
semanticscholar +1 more source
A structural polymorphism of human dopamine D2 receptor, D2(Ser311-->Cys).
Biochemical and Biophysical Research Communications - BBRC, 1993No structural change of the dopamine D2 receptor (DRD2) has been reported so far, though the DRD2 gene has been suggested to be one of the candidate genes for mental disorders.
M. Itokawa +4 more
semanticscholar +1 more source
Quantitative analysis of D2 dopamine receptor binding in the living human brain by PET.
Science, 1986D2 dopamine receptors in the putamen of living human subjects were characterized by using the selective, high-affinity D2 dopamine receptor antagonist carbon-11-labeled raclopride and positron emission tomography.
L. Farde, H. Hall, E. Ehrin, G. Sedvall
semanticscholar +1 more source
Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-vornhagen +2 more
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