Results 281 to 290 of about 169,368 (383)

Cellular Localization of Dopamine D2 Receptor Messenger RNA in the Rat Trigeminal Ganglion

open access: bronze, 1995
Robert A. Peterfreund   +2 more
openalex   +1 more source

Investigating pharmacotherapies for alcohol use disorder using Drosophila melanogaster

open access: yesAlcohol, Clinical and Experimental Research, Volume 49, Issue 10, Page 2294-2309, October 2025.
This study validates Drosophila melanogaster as a powerful model for alcohol use disorder (AUD) drug discovery. A pipeline to test drug effects on acute alcohol response, alcohol consumption, and memory for alcohol reward was developed, then validated using naltrexone and acamprosate, which effectively reduced alcohol preference and associated memory ...
Rebecca Oramas   +5 more
wiley   +1 more source

Synthetic microneurotrophins: Neurotrophin receptors for therapeutics of neurodegenerative diseases

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 19, Page 4466-4489, October 2025.
Neurodegenerative disorders are characterised by the chronic progressive degeneration of specific neuronal subtypes, neuroinflammation, myelin damage and synaptic loss. Despite their growing incidence, advancements in effective treatments remain limited, because of lack of knowledge for the aetiology of the diverse pathophysiology to design systematic ...
Ioanna Zota   +4 more
wiley   +1 more source

Critical insights into the potential risks of antipsychotic drugs to fish, including through effects on behaviour

open access: yesBiological Reviews, Volume 100, Issue 5, Page 1994-2019, October 2025.
ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett   +4 more
wiley   +1 more source

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