Results 291 to 300 of about 169,368 (383)

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

Science, 2010
E. Chien, Wei Liu, Qiang Zhao, V. Katritch, Gye Won Han, M. Hanson, Lei Shi, A. Newman, J. Javitch, V. Cherezov, R. Stevens   +10 more
semanticscholar   +1 more source

Pain Perception and Modulation: Fundamental Neurobiology and Recent Advances

European Journal of Neuroscience, Volume 62, Issue 8, October 2025.
Chronic pain is a major burden with variable treatment responses reflecting complex biopsychosocial and neurobiological factors. This narrative review synthesizes evidence on neural structures, circuits, and mediators involved in pain perception and modulation.
Willem W. J. van Strien, Markus W. Hollmann   +1 more
wiley   +1 more source

Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers

Molecular Psychiatry, 1999
E. Jönsson, M. Nöthen, F. Grünhage, L. Farde, Y. Nakashima, P. Propping, G. Sedvall   +6 more
semanticscholar   +1 more source

Propofol decreases stimulated dopamine release in the rat nucleus accumbens by a mechanism independent of dopamine D2, GABAA and NMDA receptors

, 2000
D Schulte, Luís F. Callado, Colin Davidson, Paul E. M. Phillips, Norbert Roewer, J. Schulte am Esch, Jon Stamford   +6 more
openalex   +1 more source

Synaptic Plasticity of D1 and D2 Types of Neurons in the Central Amygdala After Sucrose and Cocaine Exposure

European Journal of Neuroscience, Volume 62, Issue 8, October 2025.
D1‐type and D2‐type dopamine receptors‐expressing neurons form nonoverlapping neuronal populations in the central amygdala. Repeated exposure to sugar and cocaine alters sEPSCs frequency in an opposing way within these two neuronal populations in the central medial amygdala.
Łukasz Bijoch, Justyna Wiśniewska, Anna Beroun   +2 more
wiley   +1 more source

Dopamine receptor D2, but not D1, mediates descending dopaminergic pathway-produced analgesic effect in a trigeminal neuropathic pain mouse model. [PDF]

Pain, 2019
Liu S, Tang Y, Shu H, Tatum D, Bai Q, Crawford J, Xing Y, Lobo MK, Bellinger L, Kramer P, Tao F.   +10 more
europepmc   +1 more source

Closing the Evidence Gap: Retrospective and Prospective Strategies to Advance Aripiprazole's Potential Benefits in Patients With Cancer

Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
Elvira Meni Maria Gkrinia, Marin Golčić, Andrej Belančić   +2 more
wiley   +1 more source

Leveraging Fiber Photometry to Decipher Neural Circuits Underlying Anxiety in Mice

Fundamental &Clinical Pharmacology, Volume 39, Issue 5, October 2025.
ABSTRACT Anxiety disorders rank among the most prevalent mental health conditions worldwide, significantly affecting patients' lives. They are frequently comorbid with other psychiatric disorders, often exacerbating their severity. Current pharmacological treatments; selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines, remain limited in
Salma R. Abdennebi, Nour El Haya Touihri, Emmanuelle Corruble, Denis J. David, Indira Mendez‐David   +4 more
wiley   +1 more source

Impairment of Group I Metabotropic Glutamate Receptors in the Dorsal Striatum of the R451C‐Neuroligin 3 Mouse Model of Autism Spectrum Disorder

Journal of Neurochemistry, Volume 169, Issue 10, October 2025.
The dorsal and ventral regions of the striatum represent key brain areas for the expression of Autism Spectrum Disorder (ASD) core symptoms. In the present work, we report that different forms of long‐term synaptic plasticity are impaired in the dorsal striatum of a phenotypic mouse model of ASD, carrying the ASD‐associated R451C mutation in the ...
Maria Meringolo, Martina Montanari, Simona D'Antoni, Giuseppina Martella, Ilham El Atiallah, Giulia Ponterio, Annalisa Tassone, Ingrid Reverte, Daniele Caprioli, Georgios Strimpakos, Luisa Pieroni, Maria Vincenza Catania, Paola Bonsi   +12 more
wiley   +1 more source

Autoantibodies and Inflammation in Schizophrenia

Psychiatry and Clinical Neurosciences, Volume 79, Issue 10, Page 611-618, October 2025.
The potential role of autoantibodies in the etiology of schizophrenia is a key research focus because growing evidence suggests an association between immune dysfunction and psychotic disorders. This hypothesis is supported by findings indicating immune‐related abnormalities in patients with schizophrenia, including chronic inflammation and genetic ...
Hiroki Shiwaku
wiley   +1 more source