Results 51 to 60 of about 99,139 (322)
Analysis &Sensing, EarlyView.The graphical abstract shows an eco‐friendly approach to fabricating a biodegradable electrochemical sensor. Carbon quantum dot/nickel oxide (CQD/NiO) nanocomposites are synthesized using Aloe arborescens leaf extract, which served as a natural reducing and stabilizing agent.
Nokwanda Ngema +3 more
wiley +1 more source
npj Schizophrenia, 2017 Antipsychotic drugs are widely prescribed medications, used for numerous psychiatric illnesses. However, antipsychotic drugs cause serious metabolic side effects that can lead to substantial weight gain and increased risk for type 2 diabetes.
Zachary Freyberg, Michael J. McCarthy
doaj +1 more source
Life, 2022 Drug addiction has become a worldwide problem, affecting millions of people across the globe. While the majority of mechanistic studies on drug addiction have been focused on the central nervous system, including the mesolimbic dopamine system, the ...
Suchan Chang +9 more
doaj +1 more source
Dopamine-D1 and δ-opioid receptors co-exist in rat striatal neurons [PDF]
, 2006 Cocaine’s enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process.
Ambrose-Lanci, L. M. +3 more
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Pergolide Mesilate May Improve Fatigue in Patients with Parkinson’s Disease
Behavioural Neurology, 2002 Objectives: Fatigue is a complaint frequently encountered among patients with Parkinson’s disease (PD). Considering the possible relationship between fatigue and dopaminergic dysfuncion, we investigated the effect of pergolide mesilate (a D2 and D1 ...
Kazuo Abe +3 more
doaj +1 more source
Characterisation of the interaction of the C-terminus of the dopamine D2 receptor with neuronal calcium sensor-1. [PDF]
PLoS ONE, 2011 NCS-1 is a member of the neuronal calcium sensor (NCS) family of EF-hand Ca(2+) binding proteins which has been implicated in several physiological functions including regulation of neurotransmitter release, membrane traffic, voltage gated Ca(2 ...
Lu-Yun Lian +5 more
doaj +1 more source
Identifying Genetic Variants in Adolescents With Oppositional Defiant Disorders and/or Conduct Disorders: A Brief Report [PDF]
, 2016 PROBLEM To add to diversity in our state biobank, we explored the feasibility of collecting genetic material from adolescents with oppositional defiant disorder (ODD) and/or conduct disorder (CD) and their family members.
Carpenter, Janet S. +3 more
core +1 more source
Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Dopamine D2-receptor blockade enhances decoding of prefrontal signals in humans. [PDF]
, 2015 The prefrontal cortex houses representations critical for ongoing and future behavior expressed in the form of patterns of neural activity. Dopamine has long been suggested to play a key role in the integrity of such representations, with D2-receptor ...
Haker, Helene +4 more
core +2 more sources