Results 61 to 70 of about 265,775 (287)
The dopamine mesolimbic system is a major circuit involved in controlling goal-directed behaviors. Dopamine D2 receptors (D2R) and kappa opioid receptors (KOR) are abundant Gi protein-coupled receptors in the mesolimbic system.
Angélica Pilar Escobar +4 more
doaj +1 more source
Tailoring the Properties of Functional Materials With N‐Oxides
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich +5 more
wiley +1 more source
IntroductionAlcohol use disorder (AUD) causes significant morbidity and mortality globally. Ethanol’s rewarding and reinforcing effects are attributed to activation of the mesolimbic dopamine system, increasing accumbal dopamine release. While activation
Davide Cadeddu +7 more
doaj +1 more source
Role of D1/D2 dopamin receptors antagonist perphenazine in morphine analgesia and tolerance in rats
While opioid receptors have been implicated in the development of tolerance, the subsequent mechanisms involved in these phenomena have not been completely understood.
Ercan Ozdemir +2 more
doaj +1 more source
Actions and Consequences of Insulin in the Striatum
Insulin crosses the blood–brain barrier to enter the brain from the periphery. In the brain, insulin has well-established actions in the hypothalamus, as well as at the level of mesolimbic dopamine neurons in the midbrain.
Jyoti C. Patel +2 more
doaj +1 more source
Simulating Effects of Learning and Lesions with a Model of Intrinsic and Synaptically Gated Responses of Striatal Cholinergic Interneurons [PDF]
The giant cholinergic interneurons of the striatum are tonically active neurons (TANs) that respond with characteristic pauses to novel events and to appetitive and aversive conditioned stimuli.
Bullock, Daniel, Tan, Can Ozan
core +1 more source
Normal spatial learning and improved spatial working memory in mice (mus musculus) lacking dopamine d4 receptors [PDF]
Dopamine terminals in the hippocampus and prefrontal cortex modulate cognitive processes such as spatial learning and working memory. Because dopamine D4 receptors are expressed in these brain areas we have analyzed mutant mice lacking this receptor ...
Avale, Maria Elena +3 more
core +1 more source
The article presents nanomaterial‐integrated fiber neural probes as innovative tools for deep brain molecular sensing, neural stimulation, and temperature monitoring. It examines breakthroughs in SERS‐based biomolecule detection, thermoplasmonic activation, and luminescent thermometry, alongside strategies to overcome stability, specificity, and ...
Di Zheng +5 more
wiley +1 more source
Background Dopamine receptors comprise two subgroups, Gs protein-coupled “D1-like” receptors (D1, D5) and Gi-coupled “D2-like” receptors (D2, D3, D4). In airways, both dopamine D1 and D2 receptors are expressed on airway smooth muscle and regulate airway
Nao Matsuyama +8 more
doaj +1 more source
Dopaminergic activation of estrogen receptors induces fos expression within restricted regions of the neonatal female rat brain. [PDF]
Steroid receptor activation in the developing brain influences a variety of cellular processes that endure into adulthood, altering both behavior and physiology.
Kristin M Olesen, Anthony P Auger
doaj +1 more source

