Results 181 to 190 of about 297,910 (307)

When Safety Fails to Update: Altered Dopamine Prediction Signals in Extinction-Deficient Mice. [PDF]

eNeuro
Hanafy MK.
europepmc   +1 more source

A new glucocerebrosidase chaperone reduces α-synuclein and glycolipid levels in iPSC-derived dopaminergic neurons from patients with gaucher disease and parkinsonism [PDF]

, 2016
et al,, Fujiwara, Hideji, Ory, Daniel S, Sidhu, Rohini   +3 more
core   +1 more source

Documented End‐of‐Life Preferences of People With Parkinson's Disease or Parkinsonism Across Europe

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease and atypical parkinsonism are characterized by motor and non‐motor symptoms. As the disease advances, planning for end‐of‐life (EoL) care becomes increasingly important. However, consensus‐based European guidelines for advance care planning and documentation of EoL care preferences for parkinsonism are lacking ...
Bauke W. Dijkstra, Catharina Muente, Michela Garon, Kristina Rosqvist, Monica Scharfenort, Katharina M. Lex, Philip Poku, Eirini Nixina, Pille Taba, Ülle Krikmann, Katrin Sikk, Katie Flanagan, Anette E. Schrag, Spyros Konitsiotis, Miltiadis Makrydimas, Stefan Lorenzl, Per Odin, David J. Pedrosa, Kris C.P. Vissers, Marieke M. Groot, Bastiaan R. Bloem, Marjan J. Meinders, Angelo Antonini, the PD_Pal consortium, Argyri Tsakanika, Dhaval Trivedi, Dimitri Gatsios, Dimitrios Fotiadis, K. Ray Chaudhuri, Nikolaos Moschos, Piret Paal   +30 more
wiley   +1 more source

Prenatal valproate exposure alters midbrain and striatal neuronal morphology along with dopamine levels. [PDF]

Brain Struct Funct
Bugar Bodorova B, Havranek T, Mihalj D, Kupkova K, Bogyova E, Falougy HE, Bacova Z, Bakos J.   +7 more
europepmc   +1 more source

Computer Vision Analysis for Objective Motor Assessment in Parkinson's Disease: A Retrospective Study

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The Movement Disorder Society‐Unified Parkinson's Disease Rating Scale‐Part III (MDS‐UPDRS‐III) is subjective and insensitive to subtle changes in patients with Parkinson's disease (PD). Computer vision (CV) can extract objective kinematics from routine outpatient videos, potentially augmenting the accuracy of the motor assessment ...
Pasquale Maria Pecoraro, Luca Marsili, Antonio Cannavacciuolo, Kevin R. Duque, Jesus Abanto, Jennifer Sharma, Jennifer Scheler, Heba A. Deraz, Lauren Wingler, Vincenzo Di Lazzaro, Alberto J. Espay, Lazzaro di Biase, Matteo Bologna   +12 more
wiley   +1 more source

Methylglyoxal Affects Dopamine Homeostasis in SH-SY5Y Cells Through the Modulation of miR-190a and miR-214. [PDF]

FASEB J
Croce A, Mirra P, Pignalosa FC, Zatterale F, Prevenzano I, Conza D, Ulianich L, Miele C, Beguinot F, Fiory F.   +9 more
europepmc   +1 more source

An Unusual Motor OFF in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Shreyashi Jha, Mandar S. Jog
wiley   +1 more source

Considerations for Initiation and Maintenance of Foslevodopa/Foscarbidopa for Advanced Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background As Parkinson's disease (PD) progresses, motor fluctuations become increasingly difficult to manage with oral medications. Foslevodopa/foscarbidopa (LDp/CDp), delivered as a continuous 24‐h/day subcutaneous infusion, offers continuous levodopa delivery and stable plasma levodopa levels that reduce motor fluctuations. LDp/CDp has been
K. Ray Chaudhuri, Bruno Bergmans, Eric Freire‐Alvarez, Lucie Hopes, Drew S. Kern, Robert S. Kirsner, Giulia Lazzeri, Pedro Mendes‐Bastos, Noriko Nishikawa, Per Odin, Karolina Poplawska‐Domaszewicz, Rajesh Pahwa, Yuval Ramot, Klaus Seppi, Tobias Warnecke, Robert Wiggins, Megha B. Shah, Pavnit Kukreja, Bjoern Fritz, Koray Onuk, Stuart H. Isaacson   +20 more
wiley   +1 more source

A Review of Therapeutic Strategies to Enhance ;Neuroplasticity in Parkinson's Disease: ;Implications for Slowing Disease Progression ;and Promoting Recovery. [PDF]

Ann Neurosci
Ts S, Raj G, Kiso K.
europepmc   +1 more source

Sex-Dependent Dynamics of Behavioural and Neuropathological Changes in an A53T Alpha-Synuclein Mouse Model of Parkinson's Disease. [PDF]

Cell Mol Neurobiol
Zubelzu M, Bidgood R, Murueta-Goyena A, Ruiz-Ortega JÁ, Lafuente JV, Morera-Herreras T.   +5 more
europepmc   +1 more source