Results 201 to 210 of about 402,660 (356)

Levodopa-accelerated frailty: a hypothesis for a cumulative iatrogenic burden in Parkinson's disease. [PDF]

Front Neurol
Skaaning C.
europepmc   +1 more source

Formulation‐Dependent Cytotoxic Effects of Commercial and Analytical‐Grade Mancozeb in C6 Glial Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Mancozeb (MZ) is a widely used dithiocarbamate fungicide composed of manganese (Mn) and zinc (Zn) complexes. Increasing concern has been raised regarding its occupational and human health relevance, particularly due to its neurotoxic potential associated with Mn‐related cellular dysfunction.
Lavínia Lazzarotti, Felipe Vanz, Karina Giacomini Varela, Viviane Glaser, Diego de Carvalho, Aline Pertile Remor   +5 more
wiley   +1 more source

Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain

Proceedings of the National Academy of Sciences of the United States of America, 2016
Wen Li, E. Englund, H. Widner, B. Mattsson, D. van Westen, J. Lätt, S. Rehncrona, P. Brundin, A. Björklund, O. Lindvall, Jia-Yi Li   +10 more
semanticscholar   +1 more source

Molecular Pathogenesis of Memory Impairment in Parkinson's Disease: An Exploration of Underlying Mechanisms. [PDF]

Health Sci Rep
Pourfridoni M, Hakemi Z, Mashayekhi-Sardoo H, Baghcheghi Y.   +3 more
europepmc   +1 more source

Exploring the Role of Dysregulated Arousal in the Relationship Between Trauma and Addictive Behaviors Among College Students

Journal of Counseling &Development, EarlyView.
ABSTRACT The relationship between trauma and addictive behaviors is well‐established, yet factors mediating this relationship remain understudied. Given the prevalence of addictive behaviors among collegiate populations, we used path analysis to explore the mediating role of arousal dysregulation in the relationship between childhood trauma and a ...
Amanda L. Giordano, Kate M. Dorrough, Deborah L. Smith, Peitao Zhu   +3 more
wiley   +1 more source

Ketogenic Diet Promotes Reward Learning by Upregulating Hippocampal CAMK2A Expression and Activating Dopamine Synaptic Signaling. [PDF]

Int J Mol Sci
Qiao Y, Zeng Y, Chen C, Shen J, Wang Y, Pei P, Wang S.   +6 more
europepmc   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Dopaminergic Innervation of the Nidopallium Caudolaterale in the Japanese Quail. [PDF]

J Comp Neurol
Albayrak D, Gencturk S, Haselhuhn KB, Sevinc C, Güntürkün O, Behroozi M, Rook N, Unal G.   +7 more
europepmc   +1 more source

Reward processing in children with affective dysregulation

JCPP Advances, EarlyView.
Abstract Background Affective dysregulation (AD) in children is characterized by irritability, anger, and frequent intense temper outbursts. Considerable evidence implies altered processing of frustration about missed rewards, but few studies investigated the preceding and thus potentially predictive reward anticipation and initial delivery processing ...
Pascal‐M. Aggensteiner, Francisca Giller, Nathalie Holz, Anna Kaiser, Christine Igel, Sarah Hohmann, Manfred Döpfner, Veit Roessner, Christian Beste, Tobias Banaschewski, Daniel Brandeis, on behalf ofthe ADOPT Consortium   +11 more
wiley   +1 more source

Bridging Regenerative and Restorative Stem Cell Therapies in Parkinson's Disease. [PDF]

Cells
Onuigbo C, Martinez-Lemus J, Tharp E, Schiess M.   +3 more
europepmc   +1 more source