Results 181 to 190 of about 160,871 (266)

Intracisternal IGF-1 gene delivery attenuates early anxiety-like behavior but not dopaminergic neurodegeneration in a 6-OHDA rat model of parkinsonism. [PDF]

Front Aging Neurosci
Champarini LG, Herrera ML, Jávega Cometto M, Bartolozzi RDV, Naranjo Viteri AJ, Crespo R, Calfa GD, Hereñú CB.   +7 more
europepmc   +1 more source

Hardware Sophistications in Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease; Is the Juice Worth the Squeeze?

Movement Disorders Clinical Practice, EarlyView.
Abstract Background New sophisticated deep brain stimulation (DBS) systems enabling steering of current and aiming at improving further motor outcome and decreasing side effects have virtually replaced old omnidirectional systems, despite being more labor‐intensive and expensive.
Marwan Hariz, Patric Blomstedt
wiley   +1 more source

Reflexive eye movement alterations are related to subclinical impulsive-compulsive behaviors in Parkinson's disease. [PDF]

Neurol Sci
Hapakova L, Straka I, Necpal J, Kusnirova A, Martis P, Valkovic P, Kosutzka Z.   +6 more
europepmc   +1 more source

PREDICT‐PD: A Two‐Stage Approach to Early Identification of Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Sasivimol Virameteekul, Sheena Waters, Brook Huxford, Ashvin Kuri, Manuela Tan, Laura Pérez‐Carbonell, Eduardo de Pablo‐Fernández, Anette Schrag, Alastair J. Noyce, Cristina Simonet   +9 more
wiley   +1 more source

Precision Medicine in Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders: An Update on Emerging Treatments

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider, Divyani Garg, Vassilena Iankova, Thomas Klopstock   +3 more
wiley   +1 more source

Beyond Dopamine: Precision Pain Medicine Requires Phenotyping and Team Science, Not Just New Targets. [PDF]

Int J Spine Surg
Cruz-Almeida Y.
europepmc   +1 more source

Continuous Intrajejunal Levodopa–Carbidopa Infusion in Parkinson's Disease Associated with 22q11.2 Deletion Syndrome: A Case Series

Movement Disorders Clinical Practice, EarlyView.
Abstract Background 22q11.2 deletion syndrome (22q11DS) is a multisystem genetic disorder associated with a significantly increased risk of early‐onset Parkinson's disease (EOPD). Management is challenging because psychiatric and cognitive comorbidities often limit advanced therapies such as deep brain stimulation (DBS). Cases We report 2 patients with
Valle Victor Andrés, Jardel Amory, Hopes Lucie, Clément Guillemette, Lambert Laetitia, Becker Aurélie, Dexheimer Mylène, Bonnet Céline, Frismand Solène, Renaud Mathilde, Puisieux Salomé   +10 more
wiley   +1 more source

Regional dopaminergic dysfunction patterns discriminate Parkinson's disease from multiple system atrophy parkinsonian subtype. [PDF]

Clin Park Relat Disord
Xu D, Jia C, Zhang T, Ren C, Zhu W, Wang H, Huo L.   +6 more
europepmc   +1 more source

Use of the PROMIS and Neuro‐QoL to Evaluate Health‐Related Quality of Life following Unilateral Subthalamic Deep Brain Stimulation for Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Subthalamic nucleus deep brain stimulation (STN DBS) improves Parkinson's disease (PD)‐related motor symptoms, but how STN DBS impacts various aspects of patient‐perceived health‐related quality of life (HRQoL) is less clear. The Patient‐Reported Outcome Measurement Instrument (PROMIS) and Quality of Life in Neurological Disorders ...
Sarah A. Brinkerhoff, Frank Robinson, Roy C. Martin, Sandra Morales, Christopher L. Gonzalez, Christopher P. Hurt, Melissa Wade, Gary Cutter, Gitendra Uswatte, Harrison C. Walker, Victor A. Del Bene   +10 more
wiley   +1 more source

Dopamine and Acetylcholine in the Striatum: Circuit Interactions and Behavioral Control in Substance Use Disorders. [PDF]

Brain Sci
Dinckol O, Wenger NH, Copling A, Patel BP, Kutlu MG.   +4 more
europepmc   +1 more source