Results 211 to 220 of about 402,660 (356)

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

Sirt3 protects dopaminergic neurons from mitochondrial oxidative stress

Human Molecular Genetics, 2017
Han Shi, H. Deng, D. Gius, P. Schumacker, J. Surmeier, Yongchao C. Ma   +5 more
semanticscholar   +1 more source

When Pathways Converge: Iron, Lipid Peroxidation, and α-Synuclein in Ferroptosis-Driven Dopaminergic Neurodegeneration. [PDF]

J Neurochem
Sperlich CL, Stockwell BR, Farina M.
europepmc   +1 more source

A multimodal mutual information‐guided feature selection framework for predicting rehabilitation response in Parkinson's disease with postural instability and gait disorder

Journal of Intelligent Medicine, EarlyView.
A mutual information–guided sequential forward selection framework applied to multimodal baseline data identified key EEG and MRI features, which showed robust predictive performance across multiple machine learning models. Abstract Postural instability and gait disorder (PIGD) subtype of Parkinson's disease (PD) is marked by heterogeneous motor and ...
Yu Shi, Hongbo Zhao, Deyu Wang, Jun Pang, Hanna Lu, Xiaodong Zhu, Lin Meng   +6 more
wiley   +1 more source

PARK19 truncation mutant Dnajc6 causes lysosomal deficiency-induced upregulation of pathologic α-synuclein and neurodegeneration of substantia nigra dopaminergic cells in PARK19 knockin mice. [PDF]

NPJ Parkinsons Dis
Wang HL, Chen YL, Chiu TJ, Chiu CC, Weng YH, Liu SY, Li AH, Yeh TH.   +7 more
europepmc   +1 more source

Mapping Neurodegenerative Changes in Clinically Uncertain Parkinsonian Syndrome Patients Using Fast MR Spin TomogrAphy in Time‐Domain (MR‐STAT) Relaxometry at 3T

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MR Spin TomogrAphy in Time‐domain (MR‐STAT) enables accelerated multiparametric relaxometry (T1/T2). Previous relaxometry studies predominantly compared Parkinson's disease patients with healthy controls (HC). The potential of relaxometry to distinguish neurodegenerative from non‐neurodegenerative parkinsonism in clinically ...
Martin B. Schilder, Elon D. Wallert, Stefano Mandija, Oscar van der Heide, Hongyan Liu, Miha Fuderer, Edwin Versteeg, Jan Booij, Rob M. A. de Bie, Martijn Beudel, Henk W. Berendse, Tom van Mierlo, Jeroen Blankevoort, Cornelis A. T. van den Berg, Elsmarieke van de Giessen, Alessandro Sbrizzi   +15 more
wiley   +1 more source

Lansoprazole as a possible trigger of restless legs syndrome with suspected periodic limb movement disorder in a hemodialysis patient: a case report. [PDF]

CEN Case Rep
Nakata H, Nishiwaki K.
europepmc   +1 more source

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen, Chen‐Kai Liu, Ching‐Chung Tsai, Erna Sulistyowati, Fu‐An Li, Chung‐Jung Liu, Deng‐Chyang Wu, Shih‐Hsuan Chou, Fu‐Chen Kuo, Bin Huang   +9 more
wiley   +1 more source

Representation of spontaneous movement by dopaminergic neurons is cell-type selective and disrupted in parkinsonism

Proceedings of the National Academy of Sciences of the United States of America, 2016
Paul D. Dodson, J. Dreyer, K. Jennings, E. Syed, R. Wade-Martins, S. Cragg, J. Bolam, P. Magill, R. Malenka   +8 more
semanticscholar   +1 more source

Effects of Deep Brain Stimulation on Adductor Laryngeal Dystonia

The Laryngoscope, EarlyView.
This study evaluated how globus pallidus interna (GPi) versus ventral intermediate nucleus (VIM) deep brain stimulation (DBS) affects objective voice measures in patients with adductor laryngeal dystonia. GPi‐DBS was associated with greater improvements in voicing, voice breaks, and intensity modulation, while VIM‐DBS showed greater improvement in ...
Rita R. Patel, Maggie Stall, Stacey Halum, Benjamin Anthony, Noah Parker, Morgan Reese, David Kareken, Stephanie Dickinson, Thomas C. Witt, David A. Purger, Kunal Gupta, S. Elizabeth Zauber   +11 more
wiley   +1 more source