Results 51 to 60 of about 392,840 (300)

Steroidal anti inflammatory drug betamethasone significantly alters level of striatal dopamine in a rat model of Parkinson’s disease [PDF]

, 2008
Many scientific efforts have been well done to investigate the effects of anti inflammatory agents on the degenerative brain diseases such as Parkinson’s (PD) or Alzheimer’s disease and their affiliated sings.
Amin Geravand, Hasan Mehrab, Mehdi Shafiee Ardestani, Mostafa Saffari, Nasir Mohajer   +4 more
core   +2 more sources

Dopaminergic Mechanisms in Adhd

Pediatric Neurology Briefs, 2014
Investigators at Addenbrooke's Hospital, University of Cambridge, UK, and centers in Germany and France examined the neural mechanisms underlying attention deficits associated with ADHD and their reversal with a single dose of methylphenidate (MPH).
John Millichap, J. G. Millichap
openaire   +4 more sources

A sex difference in mouse dopaminergic projections from the midbrain to basolateral amygdala

Biology of Sex Differences, 2022
Highlights Cell-type specific labeling of VTA-to-BLA dopaminergic axons and synaptic boutons in mice The intensity of dopaminergic innervation in BLA is intermediate between those in PFC and NAC Dopaminergic axon density in BLA and the size of BLA are ...
Matthew T. C. Manion, Erica R. Glasper, Kuan Hong Wang   +2 more
doaj   +1 more source

Effect of hyperthyroidism on circulating prolactin and hypothalamic expression of tyrosine hydroxylase, prolactin signaling cascade members and estrogen and progesterone receptors during late pregnancy and lactation in the rat [PDF]

, 2017
Hyperthyroidism (HyperT) compromises pregnancy and lactation, hindering suckling-induced PRL release. We studied the effect of HyperT on hypothalamic mRNA (RT-qPCR) and protein (Western blot) expression of tyrosine hydroxylase (TH), PRL receptor (PRLR ...
Jahn, Graciela Alma, Neira, Flavia Judith, Pennacchio, Gisela Erika, Soaje, Marta, Valdez, Susana Ruth   +4 more
core   +1 more source

Fractional amplitude of low-frequency fluctuations associated with μ-opioid and dopamine receptor distributions in the central nervous system after high-intensity exercise bouts

Frontiers in Neuroimaging
IntroductionDopaminergic, opiod and endocannabinoid neurotransmission are thought to play an important role in the neurobiology of acute exercise and, in particular, in mediating positive affective responses and reward processes.
Henning Boecker, Marcel Daamen, Marcel Daamen, Angelika Maurer, Luisa Bodensohn, Judith Werkhausen, Marvin Lohaus, Christian Manunzio, Ursula Manunzio, Alexander Radbruch, Ulrike Attenberger, Juergen Dukart, Juergen Dukart, Neeraj Upadhyay   +13 more
doaj   +1 more source

IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells

Stem Cell Reports, 2017
Human pluripotent stem cell (hPSC)-derived mesencephalic dopaminergic (mesDA) neurons can relieve motor deficits in animal models of Parkinson's disease (PD).
Daniela Lehnen, Serena Barral, Tiago Cardoso, Shane Grealish, Andreas Heuer, Andrej Smiyakin, Agnete Kirkeby, Jutta Kollet, Harold Cremer, Malin Parmar, Andreas Bosio, Sebastian Knöbel   +11 more
doaj   +1 more source

Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Parkinson’s disease is characterized by the accumulation of amyloid deposits in dopaminergic neurons, mainly composed of the protein α-synuclein.
Jordi Pujols, Samuel Peña-Díaz, Diana F. Lázaro, Francesca Peccati, F. Pinheiro, Danilo González, Anita Čarija, Susanna Navarro, María Conde-Giménez, Jesús García, S. Guardiola, E. Giralt, X. Salvatella, J. Sancho, M. Sodupe, T. Outeiro, E. Dalfo, S. Ventura   +17 more
semanticscholar   +1 more source

Drug-induced Parkinson's disease modulates protein kinase A and Olfactory Marker Protein in the mouse olfactory bulb [PDF]

, 2017
Background Olfaction is often affected in parkinsonian patients, but dopaminergic cells in the olfactory bulb are not affected by some Parkinson-inducing drugs.
Caretta, Antonio, Mucignat, Carla
core   +2 more sources

Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex

Journal of Neuroscience, 1997
Subanesthetic doses of ketamine, a noncompetitive NMDA receptor antagonist, impair prefrontal cortex (PFC) function in the rat and produce symptoms in humans similar to those observed in schizophrenia and dissociative states, including impaired ...
B. Moghaddam, Barbara W. Adams, A. Verma, D. Daly   +3 more
semanticscholar   +1 more source

Evaluation of the Association Between Serum Levels of Testosterone and Prolactin With 6- Hydroxydopamine- Induced Parkinsonism in Male Rats

Basic and Clinical Neuroscience, 2021
Introduction: Parkinson’s Disease (PD) associates with changes in sex hormones; however, it remains unknown whether this is either a cause for or a result of the disease.
Roghaieh Razaghi, Hossein Piri, Hanieh Jafari, Nafiseh Rastgoo, Mohammad Ali Hosseini, Hashem Haghdoost – Yazdi   +5 more
doaj