Results 61 to 70 of about 134,791 (125)
High level modeling of tonic dopamine mechanisms in striatal neurons [PDF]
arXiv, 2007 The extant versions of many basal ganglia models use a `gating' model of dopamine function which enhances input to D1 receptor units and attenuates input to D2 receptor units. There is evidence that this model is unsatisfactory because (a) there are not sufficient dopaminergic synapses to gate all input and (b) dopamine's main effect is likely to be on
arxiv
Compromised Dynamic Cerebral Autoregulation in Patients with Restless Legs Syndrome
Nature and Science of SleepYanan Zhang,1 Qianqian Chen,1 Qingqing Sun,1 Mingyang Tang,1 Yi Yang,1,2 Zhen-Ni Guo,1,2 Zan Wang1,2 1Sleep Center, Department of Neurology, The First Hospital of Jilin University, Chang Chun, People’s Republic of China; 2Stroke Center, Department of ...
Zhang Y +6 more
doaj
Computational Psychiatry, 2018 Patients with Parkinson’s disease (PD) are often treated with dopaminergic medication. Dopaminergic medication is known to improve both motor and certain nonmotor symptoms, such as depression.
Monique H. M. Timmer +4 more
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Co-operativity in neurons and the role of noise in brain [PDF]
arXiv, 2007 In view of some recent results in case of the dopaminergic neurons exhibiting long range correlations in VTA of the limbic brain we are interested to find out whether any stochastic nonlinear response may be reproducible in the nano scales usimg the results of quantum mechanics.
arxiv
Biology Open, 2016 Notch signalling is a well-established pathway that regulates neurogenesis. However, little is known about the role of Notch signalling in specific neuronal differentiation.
Niurka Trujillo-Paredes +8 more
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Biophysics of risk aversion based on neurotransmitter receptor theory [PDF]
Neuro Endocrinol Lett. 2008 Aug;29(4):399-404.
http://node.nel.edu/?node_id=7744, 2011 Decision under risk and uncertainty has been attracting attention in neuroeconomics and neuroendocrinology of decision-making. This paper demonstrated that the neurotransmitter receptor theory-based value (utility) function can account for human and animal risk-taking behavior.
arxiv
Neural Regeneration ResearchParkinson’s disease is primarily caused by the loss of dopaminergic neurons in the substantia nigra compacta. Ferroptosis, a novel form of regulated cell death characterized by iron accumulation and lipid peroxidation, plays a vital role in the death of ...
Zhihao Lin +8 more
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Reinforcement learning with a network of spiking agents [PDF]
arXiv, 2019 Neuroscientific theory suggests that dopaminergic neurons broadcast global reward prediction errors to large areas of the brain influencing the synaptic plasticity of the neurons in those regions. We build on this theory to propose a multi-agent learning framework with spiking neurons in the generalized linear model (GLM) formulation as agents, to ...
arxiv
Parkinson's Disease Assessment from a Wrist-Worn Wearable Sensor in Free-Living Conditions: Deep Ensemble Learning and Visualization [PDF]
arXiv, 2018 Parkinson's Disease (PD) is characterized by disorders in motor function such as freezing of gait, rest tremor, rigidity, and slowed and hyposcaled movements. Medication with dopaminergic medication may alleviate those motor symptoms, however, side-effects may include uncontrolled movements, known as dyskinesia.
arxiv
Bio-Protocol, 2018 The nematode Caenorhabditis elegans is a powerful genetic model that can be used to investigate neuronal death. Research using C. elegans has been crucial to characterize cell death programmes that are conserved in mammals.
Sarah-Lena Offenburger, Anton Gartner
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