Results 251 to 260 of about 116,827 (301)

Rethinking Mitochondrial Parkinson's Disease in the α‐Synuclein Seed Amplification Assays Era

Movement Disorders, EarlyView.
Marco Percetti, Vidal Yahya, Alessio Di Fonzo, Edoardo Monfrini   +3 more
wiley   +1 more source

Optimizing Differentiation Protocols for Producing Dopaminergic Neurons from Human Induced Pluripotent Stem Cells for Tissue Engineering Applications

Biomarker Insights, 2015
Meghan Robinson, Suk-yu Yau, Lin Sun, Nicole Gabers, Emma Bibault, Brian R. Christie, Stephanie M. Willerth   +6 more
doaj  

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Dopaminergic neurons

The International Journal of Biochemistry & Cell Biology, 2005
Dopaminergic neurons of the midbrain are the main source of dopamine (DA) in the mammalian central nervous system. Their loss is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons are found in a 'harsh' region of the brain, the substantia nigra pars compacta, which is DA-rich and ...
Shankar J, Chinta, Julie K, Andersen
openaire   +2 more sources

Dopaminergic neurons intrinsic to the striatum

Journal of Neurochemistry, 2007
AbstractThe striatum – the largest integrative component of the basal ganglia – harbors a population of neurons that express the enzyme tyrosine hydroxylase (TH), a faithful marker of dopaminergic neurons. The dopaminergic nature of these neurons is further supported by the fact that they express the dopamine (DA) transporter (DAT) and the nuclear ...
Philippe, Huot, André, Parent
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Toxicity of semaphorin3A for dopaminergic neurons

Neuroscience Letters, 2005
Semaphorin3A (Sema3A) is known to cause neuronal apoptosis and serves as a chemorepellent factor for axonal growth. In our previous report, we found that Sema3A was up-regulated in the 6-OHDA-injected striatum of rats, suggesting that Sema3A was likely involved in dopaminergic (DA) depletion.
Takao, Yasuhara, Tetsuro, Shingo, Kenichiro, Muraoka, Masahiro, Kameda, Takashi, Agari, Yuan, Wenji, Tomohito, Hishikawa, Toshihiro, Matsui, Yasuyuki, Miyoshi, Toru, Kimura, Cesario V, Borlongan, Isao, Date   +11 more
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Dopaminergic neurons in the human retina

Journal of Comparative Neurology, 1982
AbstractThe utilization of dopamine in the adult human retina was examined by using high‐affinity uptake, localization, synthesis, and release as neurotransmitter‐specific physiological probes. Autoradiographic and histochemical studies have shown that dopamine‐accumulating and dopamine‐containing cells of the human retina belong to a population of ...
J M, Frederick, M E, Rayborn, A M, Laties, D M, Lam, J G, Hollyfield   +4 more
openaire   +2 more sources

Dopaminergic Dependency of Cholinergic Pallidal Neurons

Neuroscience, 2023
We employed the whole-cell patch-clamp method and ChAT-Cre mice to study the electrophysiological attributes of cholinergic neurons in the external globus pallidus. Most neurons were inactive, although approximately 20% displayed spontaneous firing, including burst firing.
Janintzitzic López-Niño, Montserrat Padilla-Orozco, Aidán Ortega, Verónica Alejandra Cáceres-Chávez, Dagoberto Tapia, Antonio Laville, Elvira Galarraga, José Bargas   +7 more
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Dopaminergic neurons for Parkinson's therapy

Nature Biotechnology, 2012
A differentiation protocol guided by developmental principles produces more-authentic dopaminergic neurons for transplantation in patients.
openaire   +1 more source

Noradrenergic Modulation on Dopaminergic Neurons

Neurotoxicity Research, 2018
It is now well accepted that there is a close relationship between noradrenergic and dopaminergic neurons in the brain, especially referring to the modulation of the locus coeruleus-norepinephrine (LC-NE) system on dopamine transmission. The disturbance of this modulation may contribute to neurodegeneration of dopaminergic neurons in Parkinson's ...
openaire   +3 more sources