Results 101 to 110 of about 16,506,777 (367)

Dehydroepiandrosterone (DHEA) supplementation in diminished ovarian reserve (DOR)

Reproductive Biology and Endocrinology, 2011
BackgroundWith infertility populations in the developed world rapidly aging, treatment of diminished ovarian reserve (DOR) assumes increasing clinical importance.
N. Gleicher, D. Barad
semanticscholar   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Evaluation of anesthesiology residents in the diagnosis and control of malignant hyperthermia: comparison of three scenarios of realistic simulation ‒ a cross-sectional controlled study

Brazilian Journal of Anesthesiology
Introduction: Simulation-based training is particularly beneficial for rare and life-threatening diseases such as Malignant Hyperthermia (MH). In addition, cognitive aids, including flowcharts and checklists, can be used as guidance in crisis, reducing ...
Mariana F.L. Neville, Victor Guimarães de Almeida, Pamela Vieira Andrade, Joilson Moura Santos, Masashi Munechika, David Ferez, Mary dos Santos Silva, Leonardo Ayres Canga, Ana Cristina Tripoloni, Thierry Girard, Helga Cristina Almeida da Silva   +10 more
doaj   +1 more source

Peripheral nerve block and rebound pain: literature review

Brazilian Journal of Anesthesiology, 2019
Background and objectives: To investigate, describe, and assess the phenomenon of “rebound pain” as a clinically relevant problem in anesthetic practice. Content: The phenomenon of “rebound pain” has been demonstrated and described as a very severe pain,
Layana Vieira Nobre, Graziella Prianti Cunha, Paulo César Castello Branco de Sousa, Alexandre Takeda, Leonardo Henrique Cunha Ferraro   +4 more
doaj   +1 more source

Preoperative frailty assessment: just do it! [PDF]

, 2023
Daniel I. McIsaac, Alexa Grudzinski, Sylvie Aucoin   +2 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Pain management in children with erythromelalgia: case report

Brazilian Journal of Anesthesiology, 2018
Erythromelalgia is a neuropathic pain syndrome due to an autosomal dominant gene, characterized by erythema, increased skin temperature and burning pain in hands and feet, whose treatment is often unsatisfactory.
Estela Irene Bortoli, Rioko Kimiko Sakata   +1 more
doaj   +1 more source

CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq

Genome Biology, 2016
Single-cell transcriptomics requires a method that is sensitive, accurate, and reproducible. Here, we present CEL-Seq2, a modified version of our CEL-Seq method, with threefold higher sensitivity, lower costs, and less hands-on time.
T. Hashimshony, N. Senderovich, Gal Avital, A. Klochendler, Yaron de Leeuw, Leon Anavy, David G Gennert, Shuqiang Li, K. Livak, O. Rozenblatt-Rosen, Y. Dor, A. Regev, I. Yanai   +12 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Neurociência da dor: exercícios para dor crônica

Estudios y Perspectivas Revista Científica y Académica
Introdução: Na dor crônica, o sistema nervoso muitas vezes se torna hiperativo, gerando dor persistente e debilitante. Compreender os mecanismos neurobiológicos por trás da dor crônica é crucial para desenvolver tratamentos mais eficazes. Objetivo: Compreender a importância da neurociência relacionando para os exercícios para dor crônica.
LUIZ FELIPE CHAVES CARVALHO, FABIANO DE ABREU AGRELA RODRIGUES   +1 more
openaire   +1 more source