Results 101 to 110 of about 3,618,545 (328)

PATOFISIOLOGIA DA DOR

open access: yesArchives of Veterinary Science, 2008
A dor pode ser definida como uma experiênciasensorial e emocional desagradável, associadaa uma lesão real ou potencial. A dor fisiológicaé um reflexo protetor do organismo, para evitaruma injúria ou dano tecidual. Frente à lesão teciduala dor patológica providenciará condições para acicatrização. Uma vez instalada a injúria pode se introduziro conceito
A F P F Wouk, T Sillas, P R Klaumann
openaire   +3 more sources

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga   +8 more
wiley   +1 more source

Ultrasound-guided peripheral nerve blocks in anticoagulated patients – case series

open access: yesBrazilian Journal of Anesthesiology, 2017
Background and objectives: The advent of ultrasound has brought many benefits to peripheral nerve blocks. It includes both safety and effectiveness, given the possibility of visualizing the neurovascular structures and the needle during the procedure ...
Luis Eduardo Silveira Martins   +4 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Does Managerial 'Outsourcing' Reduce Expense Preference Behavior? A Comparison of Adopters and Non-Adopters of Contract-Management in US Hospitals [PDF]

open access: yes
This paper explores potential realization of gains by hospitals that are managed on a day-to-day basis by external organizations under formal contracts.
Avi Dor, Kathleen Carey
core  

GÊNERO E DOR

open access: yesIPOTESI – REVISTA DE ESTUDOS LITERÁRIOS, 2020
Tradução de Género y dolor. Neste ensaio a escritora chilena Diamela Eltit elabora uma reflexão acerca do ensaio e pesquisa acadêmicos. O texto foi publicado pela primeira vez em 2013 na revista Taller de Letras 53 e, posteriormente, integrado à sua coletânea de ensaios Réplicas publicada em 2016.
openaire   +2 more sources

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla   +15 more
wiley   +1 more source

Spacecraft-spacecraft very long baseline interferometry. Part 1: Error modeling and observable accuracy [PDF]

open access: yes
In Part 1 of this two-part article, an error budget is presented for Earth-based delta differential one-way range (delta DOR) measurements between two spacecraft.
Border, J. S., Edwards, C. D., Jr.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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