Results 181 to 190 of about 653,638 (208)
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Neuromodulation in chronic insomnia: Targeting the dorsal raphe nucleus

Sleep Medicine
Chronic insomnia is a prevalent disabling disorder that disrupts sleep patterns, mental health and cognitive processes. Although standard treatments, including cognitive-behavioral therapy for insomnia (CBT-I) and medications, treat the disorder in some patients, their use is curtailed by poor adherence or tolerance to adverse effects or only partial ...
Hema kumari Jeswani, Sanhia Maheshwari
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Regulation of nucleus accumbens dopamine release by the dorsal raphe nucleus in the rat

Neurochemical Research, 1992
The effects of microinfusing L-glutamate, serotonin (5-HT), (+-)-8-hydroxy-2-(di-N-propylamino) tetralin (8-OH DPAT; a 5-HT1A agonist), and muscimol (a GABAA agonist) into the dorsal raphe nucleus on the extracellular levels of 5-HT, dopamine (DA) and their metabolites in the nucleus accumbens were studied in unanesthetized, freely moving, adult male ...
K, Yoshimoto, W J, McBride
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Effects of stimulating the dorsal raphe nucleus of the rat on neuronal activity in the dorsal lateral geniculate nucleus

Brain Research, 1989
The effect of stimulating the dorsal raphe nucleus (DRN) on the activity of single relay neurons in the dorsal lateral geniculate nucleus (LGNd) was studied in rats anesthetized with urethane. The position of stimulating electrodes was confirmed on histological sections processed with NADPH-diaphorase histochemistry which could delineate the DRN ...
Y, Kayama   +3 more
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The median raphe nucleus participates in the depressive-like behavior induced by MCH: Differences with the dorsal raphe nucleus

Peptides, 2013
An emerging body of evidence involves the hypothalamic neuropeptide melanin-concentrating hormone (MCH) in the regulation of emotional states. We have reported a pro-depressive effect induced by MCH after its microinjection into the dorsal raphe nucleus (DR) evaluated in the forced swimming test (FST) in rats.
Ximena, López Hill   +4 more
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Serotoninergic projections from the dorsal raphe nucleus to the nucleus submedius in the rat and cat

Neuroscience, 1993
The nucleus submedius in the medial thalamus has been known to receive spinothalamic and trigeminothalamic fibers, and to contain neurons which can be activated by noxious stimuli. These previous findings suggest that the nucleus submedius may be involved in the processing and relay of pain-related information.
S, Matsuzaki   +4 more
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Lower brainstem catecholamine afferents to the rat dorsal raphe nucleus

The Journal of Comparative Neurology, 1996
A large body of data suggests that the activation of alpha 1 receptors by a tonic noradrenergic input might be responsible for the tonic discharge of the serotonergic neurons of the dorsal raphe nucleus (DRN). To test this hypothesis, it was necessary to determine the origin of the noradrenergic and adrenergic innervation of these neurons.
Peyron, Christelle   +4 more
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Blockade by naltrexone of analgesia produced by stimulation of the dorsal raphe nucleus

Pharmacology Biochemistry and Behavior, 1981
Naloxone blockade of stimulation-produced analgesia in the rat is partial and variable. In the present study the effectiveness of the long-acting narcotic antagonist naltrexone is examined. Bipolar stainless steel electrodes were implanted in the dorsal raphe nucleus or ventral periaqueductal gray matter of male rats.
A R, Swajkoski, D J, Mayer, J H, Johnson
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Transcriptional Landscape of the Dorsal Raphe Nucleus

2020
The dorsal raphe nucleus (DRN) is a major source of neuromodulators in the brain that has been implicated in a wide range of neurological and psychiatric disorders. However, little is known about how dysfunction of DRN neurons causes behavioral deficits. The DRN is the largest of the serotonergic nuclei housing approximately a third of all serotonergic
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Serotonergic activity in rat cerebral arteries depends on dorsal raphe nucleus but not on median raphe nucleus.

Revista espanola de fisiologia, 1995
The effect of Chlorimipramine and Muscimol on serotonergic activity in rat cerebral arteries and in dorsal and median raphe nuclei were used to study the presence of a serotonergic innervation in the cerebral blood vessels functionally dependent on the brainstem nuclei activity.
M J, Moreno   +4 more
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