Results 11 to 20 of about 1,233,920 (254)

Post-Inhibitory Rebound Firing of Dorsal Root Ganglia Neurons

Journal of Pain Research, 2022
Tong Zhu,1,2 Siqi Wei,1 Yuying Wang1,3,4 1Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, Shaanxi, 710061, People’s Republic of China; 2Clinical Experimental Center ...
Zhu T, Wei S, Wang Y
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Expression of neuropeptides – galanin and Reg2 - in subcategories of nociceptors after nerve injury [PDF]

, 2010
PhDNeuropeptides show dynamic changes in expression after nerve injury, and have been implicated in chronic pain states. I sought to compare expression of two peptides which are upregulated after nerve injury, galanin and Reg2, and to determine the ...
Burrows, Karen Lynne
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Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia [PDF]

, 2009
The peripheral nervous system (PNS) of higher vertebrates is segmented to align the spinal nerve roots with the vertebrae. This co-patterning is set up during embryogenesis, when vertebrae develop from the sclerotome layer of the metameric somites, and ...
Maden, CH, Christiana Ruhrberg, Quenten Schwarz, Davidson, K., Schwarz, Q, Ruhrberg, C., Kathryn Davidson, Maden, C., Davidson, K, Ruhrberg, C, Schwarz, Q., Charlotte H. Maden   +11 more
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Mechanisms involved in chronic neuropathic pain after avulsion injury [PDF]

, 2010
PhDMotor vehicle accidents are the most common cause of injuries involving avulsion of spinal roots from the brachial or lumbosacral plexuses. This results in chronic intractable pain that is refractory to pharmacotherapy.
Chew, Daniel John
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Molecular pathways of proprioceptive dorsal root ganglion (DRG) sensory neuron specification [PDF]

, 2005
Dorsal root ganglia (DRG) sensory neurons can be classified into distinct neuronal subpopulations based on the expression of specific receptor tyrosine kinases known as neurotrophic factor receptors.
Kramer, Ina
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Intense isolectin-B4 binding in rat dorsal root ganglion neurons distinguishes c-fiber nociceptors with broad action potentials and high nav1.9 expression [PDF]

, 2006
Binding to isolectin-B4 (IB4) and expression of tyrosine kinase A (trkA) (the high-affinity NGF receptor) have been used to define two different subgroups of nociceptive small dorsal root ganglion (DRG) neurons. We previously showed that only nociceptors
Fang, Xin, Dr., Fang, Xin, McMullan, Simon, Lawson, Sally N, Fang, X, Djouhri, L, Lawson, Sally N., Berry, Carol, Waxman, Stephen G., Okuse, K, McMullan, S, Djouhri, Laiche, Berry, CM, Waxman, SG, Waxman, Stephen G, Berry, C. M, Okuse, Kenji, Lawson, SN   +17 more
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Morphology and Nanomechanics of Sensory Neurons Growth Cones following Peripheral Nerve Injury [PDF]

, 2012
A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re ...
Vivien Szabo, Scamps, Frédérique, Végh Attila-Gergely, Attila-Gergely Végh, Lucas Olivier, Scamps Frédérique, Ouafa Benzina, Thierry Cloitre, Csilla Gergely, Benzina Ouafa, Szabo, Vivian, Szabo, Vivien, Cloitre, Thierry, Marta Martin, Gergely, Csilla, Frédérique Scamps, Szabo Vivien, Cloitre Thierry, Olivier Lucas, Gergely Csilla, Benzina, Ouafa, Lucas, Olivier, Martin Marta, Martin, Marta, Végh, Attila Gergely   +24 more
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Suppression of histone deacetylases by SAHA relieves bone cancer pain in rats via inhibiting activation of glial cells in spinal dorsal horn and dorsal root ganglia

Journal of Neuroinflammation, 2020
Background Robust activation of glial cells has been reported to occur particularly during the pathogenesis of bone cancer pain (BCP). Researchers from our group and others have shown that histone deacetylases (HDACs) play a significant role in ...
Xiao-Tao He, Xiao-Fan Hu, Chao Zhu, Kai-Xiang Zhou, Wen-Jun Zhao, Chen Zhang, Xiao Han, Chang-Le Wu, Yan-Yan Wei, Wei Wang, Jian-Ping Deng, Fa-Ming Chen, Ze-Xu Gu, Yu-Lin Dong   +13 more
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Stem cells from wildtype and Friedreich's ataxia mice present similar neuroprotective properties in dorsal root ganglia cells.

PLoS ONE, 2013
Many neurodegenerative disorders share a common susceptibility to oxidative stress, including Alzheimer's, Parkinson Disease, Huntington Disease and Friedreich's ataxia.
Jonathan Jones, Alicia Estirado, Carolina Redondo, Salvador Martinez, Salvador Martinez   +4 more
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Somatic instability of the expanded GAA triplet-repeat sequence in Friedreich ataxia progresses throughout life [PDF]

, 2007
Friedreich ataxia (FRDA) patients are homozygous for expanded GAA triplet-repeat alleles in the FXN gene. Primary neurodegeneration involving the dorsal root ganglia (DRG) results in progressive ataxia.
Ramussen, A, De Biase, Irene, Monticelli, A, Bidichandani, Sanjay I., De Biase, I, Al-Mahdawi, S, Pook, Mark, Cocozza, S, Al-Mahdawi, Sahar, Pook, M A, Bidichandani, S, Monticelli, Antonella, Rasmussen, Astrid, Cardone MF, RASMUSSEN A, D'ADDABBO, PIETRO, Teti MG, POOK M, Misceo D, MONTICELLI A, ARCHIDIACONO, Nicoletta, VENTURA, MARIO, BIDICHANDANI SI, ROCCHI, Mariano, COCOZZA, SERGIO, Capozzi O, Lomiento M, DE BIASE I, AL MAHDAWI S, Roberto R   +29 more
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